Tolvaptan

Uses

Tolvaptan Uses Tolvaptan is used in the treatment of the syndrome of inappropriate antidiuretic hormone secretion (SIADH) and low sodium levels in the blood. It addresses low sodium levels, which can result from conditions such as heart failure, cirrhosis, and SIADH.

How it Works

How Tolvaptan works Tolvaptan is a vasopressin antagonist. It functions by blocking the effects of the hormone vasopressin in the body. This action increases urine production, reduces the amount of water in the blood, and raises the blood sodium level.

Side Effects

Common side effects of Tolvaptan include dryness in the mouth, increased thirst, dizziness, nausea, fatigue, polyuria, and diarrhea.

Expert Advice

Tolvaptan treats low sodium levels in the blood.
It improves urine flow without causing excessive sodium loss during urination.
Take it at the same time every day.
Follow the dose and duration prescribed by your doctor.
To avoid dehydration, drink fluids as soon as you feel thirsty, but avoid alcoholic beverages.
Do not take Tolvaptan if you:

Are unable to urinate
Cannot recognize when you are thirsty
Are severely dehydrated

You will need to be hospitalized under observation whenever you start or restart treatment with Tolvaptan.
Inform your doctor if you notice:

Problems with speech or muscle control
Trouble swallowing
Trouble moving your arms and legs
Mood changes

Your doctor may check your liver function before starting treatment and regularly thereafter.
Inform your doctor if you notice:

Yellowing of the eyes or skin
Dark urine
Stomach pain

Other Combinations

Frequently asked questions

How long should I take Tolvaptan?

Tolvaptan is typically prescribed for a maximum of 30 days to correct sodium levels. Consult your doctor about stopping the medication once sodium levels normalize.

Who should avoid taking Tolvaptan?

Tolvaptan should not be taken by individuals with low sodium levels, those unable to replace fluids, patients with impaired kidney function due to fluid loss, those who cannot sense thirst or dizziness, individuals allergic to Tolvaptan, or those on medications that interfere with Tolvaptan's effectiveness.

Does Tolvaptan affect blood sugar levels?

Yes, Tolvaptan may increase blood sugar levels. Patients with diabetes should monitor their blood sugar closely while taking this medication.

What should I do if I take an overdose of Tolvaptan?

Seek urgent medical attention immediately if you suspect an overdose. Symptoms may include excessive thirst, dry skin, sunken eyes, rapid heartbeat, shallow breathing, low blood pressure, increased urination, and fainting.

Can I consume grapefruit juice while taking Tolvaptan?

No, grapefruit and grapefruit juice should be avoided while taking Tolvaptan, as they can increase Tolvaptan levels in the blood and cause sodium levels to rise too rapidly.

What important information should I know while taking Tolvaptan?

Tolvaptan can cause sodium levels in your blood to rise too quickly, potentially leading to osmotic demyelination syndrome (ODS), which may result in serious nerve damage, coma, or death. Symptoms of ODS include difficulty speaking or swallowing, drowsiness, confusion, mood changes, seizures, involuntary movements, and muscle weakness.

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