Tocilizumab

Uses

Tocilizumab is used in the treatment of ulcerative colitis, Crohn's disease, psoriasis, ankylosing spondylitis, and rheumatoid arthritis.

How it Works

Tocilizumab works by blocking the action of specific chemical messengers responsible for inflammation, swelling, and redness associated with certain joint diseases.

Side Effects

Common side effects of Tocilizumab include headache, high blood pressure, upper respiratory tract infection, and injection site reactions such as pain, swelling, and redness.

Expert Advice

Tocilizumab is administered as a drip (intravenous infusion) or as an injection directly into a vein.
You may be required to undergo regular blood tests to monitor:

Blood counts
Cholesterol levels
Liver function

This medication may cause dizziness. If you experience this, avoid driving or operating machinery.
Tocilizumab can impair your ability to fight infections. Notify your doctor if you experience:

Fever
Cough
Stomach pain

Inform your doctor if you are pregnant, planning to become pregnant, or are breastfeeding.
Do not discontinue the medication without consulting your doctor first.

Other Combinations

Frequently asked questions

Who should avoid Tocilizumab treatment?

Tocilizumab should not be administered to patients with a history of abnormal liver enzyme levels, low platelet counts, active tuberculosis, or any active bacterial or viral infections. It is also contraindicated in pregnant or breastfeeding individuals due to potential complications.

Is Tocilizumab suitable for all Covid-19 patients?

No, Tocilizumab is not suitable for all Covid-19 patients due to potential health risks, including serious infections and prolonged viral shedding. It should only be administered when the benefits outweigh the risks.

What are the side effects associated with Tocilizumab?

Side effects of Tocilizumab may include anaphylaxis, transaminitis, leukopenia, neutropenia, and an increased risk of serious bacterial and viral infections, including reactivation of tuberculosis.

Who should receive Tocilizumab for Covid-19 treatment?

Tocilizumab is indicated for patients with moderate to severe Covid-19 who experience worsening hypoxia despite 24 to 48 hours of corticosteroid treatment and supportive care.

What should be done if there is no improvement after Tocilizumab treatment?

If no improvement is observed after Tocilizumab, the doctor will determine the next steps. While Tocilizumab can reduce lung inflammation, it does not reverse existing damage. Persistent symptoms may necessitate evaluation for other pulmonary or cardiac issues and treatment for any new bacterial infections.

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