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Tipiracil + Trifluridine

Uses

Tipiracil and Trifluridine Uses Tipiracil and Trifluridine are used in the treatment of colon and rectal cancer.

How it Works

How Tipiracil and Trifluridine work Tipiracil and Trifluridine is a combination of two anticancer medications. Trifluridine inhibits DNA synthesis and halts the growth of cancer cells. Tipiracil reduces the degradation of trifluridine in the body.

Side Effects

Common side effects of Tipiracil and Trifluridine include anemia (low red blood cell count), decreased white blood cell count (neutrophils), fatigue, nausea, low platelet count, decreased appetite, diarrhea, fever, and vomiting.

Expert Advice

  • Avoid the use of antacids within two hours of taking this medicine.
  • Drink plenty of water every 24 hours after the start of the treatment.
  • You may be at risk of infection; therefore, try to avoid crowds or individuals with colds, and report fever or any other signs of infection immediately to your doctor.
  • To help treat/prevent mouth sores:
    • Use a soft toothbrush.
    • Rinse your mouth at least 3 times a day with saline water.
  • To reduce nausea:
    • Take anti-nausea medications as prescribed by your doctor.
    • Eat small, frequent meals.
  • Consume foods that may help reduce diarrhea and ensure adequate rest.
  • Use contraceptives, and do not conceive a child (get pregnant) while taking Tipiracil + Trifluridine.
  • Barrier methods of contraception, such as condoms, should be used during therapy and for 6 months after treatment.

Other Combinations

Related Medications

Frequently asked questions

Breastfeeding is not recommended during treatment with Tipiracil+Trifluridine and for 1 day after the final dose.
Tipiracil+Trifluridine may harm a developing fetus. It is crucial to avoid conception during treatment and for at least 6 months post-treatment. Discuss effective contraception with your doctor before starting the treatment.
Continue taking Tipiracil+Trifluridine as prescribed. Regular scans will assess your tumor's response, and your doctor will schedule these scans.
Bleeding gums may result from a decrease in platelet count, which is essential for blood clotting.
Gentle exercise may help alleviate tiredness, but consult your doctor before starting any exercise regimen.
You can maintain your regular diet unless advised otherwise by your doctor. It is recommended to sip water regularly, eat small and nourishing snacks frequently, and use hard candy or popsicles to help with nausea.
To relieve diarrhea, consume foods high in soluble fiber, such as ripe bananas, oranges, boiled potatoes, white rice, curd, and oatmeal. Stay hydrated by drinking 8-10 glasses of water daily and consider soups and juices.
Tipiracil+Trifluridine can lower white blood cell and platelet counts, increasing infection risk. Avoid contact with infected individuals and consult your doctor if you suspect an infection or experience fever, chills, or cough.
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