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Tetrabenazine

Uses

Tetrabenazine is used in the treatment of Huntington's disease.

How it Works

How Tetrabenazine works: Tetrabenazine functions by depleting the stores of specific chemical messengers in the brain that are responsible for controlling body movements.

Side Effects

Common side effects of Tetrabenazine include insomnia (difficulty sleeping), anxiety, depression, drowsiness, gastrointestinal disturbances, and respiratory tract infections.

Expert Advice

  • You have been prescribed Tetrabenazine to help control movement disorders, such as those seen in Huntington’s disease.
  • Exercise caution while driving or engaging in activities that require concentration, as Tetrabenazine may cause dizziness and sleepiness.
  • Inform your doctor if you experience symptoms such as:
    • High fever
    • Excessive sweating
    • Muscle stiffness
    • Rapid breathing
    These symptoms may indicate a rare side effect known as neuroleptic malignant syndrome.
  • Notify your doctor if you notice any unusual changes in mood or behavior, including:
    • New or worsening depression
    • Suicidal thoughts or behavior
  • Do not discontinue Tetrabenazine without consulting your doctor first, as this may lead to a worsening of symptoms.

Other Combinations

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Frequently asked questions

No, Tetrabenazine should be swallowed whole and not crushed, cut, or chewed. If you have difficulty swallowing the tablet, consult your doctor for alternatives.
Tetrabenazine is not an antipsychotic; it is a vesicular monoamine transporter 2 (VMAT2) inhibitor that alters certain brain substances affecting muscles and nerves.
Yes, Tetrabenazine can lower blood pressure, potentially causing dizziness, lightheadedness, or fainting when standing up quickly. To mitigate this, rise slowly from a lying position.
No, do not abruptly stop taking Tetrabenazine without consulting your doctor, as it may lead to neuroleptic malignant syndrome. Your doctor will help you taper the dosage safely.
Avoid alcohol while taking Tetrabenazine, as it may increase sleepiness. Consult your doctor about any other medications that may cause similar effects.
Avoid driving or operating heavy machinery if you experience sleepiness while taking Tetrabenazine.
Tetrabenazine may increase the risk of depression or suicidal thoughts in patients with Huntington’s disease. It should not be taken if you have Huntington’s disease and depression.
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