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Suxamethonium

Uses

Suxamethonium is used for skeletal muscle relaxation during surgery.

How it Works

How Suxamethonium works Suxamethonium relaxes the muscles by blocking nerve impulses.

Side Effects

Common side effects of Suxamethonium include rash, increased intraocular pressure, elevated potassium levels in the blood, postoperative muscle pain, slow heart rate, tachycardia, skin flushing, muscle twitching, myoglobinemia, and myoglobinuria.

Expert Advice

  • Suxamethonium is administered as an injection into a vein under the supervision of a doctor.
  • This medication may cause dizziness or drowsiness.
  • Do not drive until you are aware of how Suxamethonium affects you.
  • Your doctor will regularly monitor your blood pressure, as this medication may lead to elevated blood pressure.
  • Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Other Combinations

Frequently asked questions

Is Suxamethonium reversible?
Suxamethonium is a short-acting muscle relaxant with a depolarizing effect at the neuromuscular junction that is not pharmacologically reversible.
Is Suxamethonium still used?
Yes, Suxamethonium is still utilized during general anesthesia.
What is Suxamethonium apnoea?
Suxamethonium apnoea occurs when a patient lacks the enzymes to metabolize the drug, resulting in prolonged paralysis and inadequate breathing after anesthesia.
What is Suxamethonium sensitivity?
Suxamethonium sensitivity refers to a prolonged effect of the drug, resulting in extended muscle relaxation.
Does Suxamethonium cross the placenta?
At normal therapeutic doses, Suxamethonium does not cross the placental barrier in significant amounts.
Why does Suxamethonium cause bradycardia?
Suxamethonium can cause bradycardia due to its initial metabolite stimulating muscarinic receptors in the sinus node, leading to a transient negative chronotropic effect. This can be treated with atropine if it occurs with repeated dosing.
Why does Suxamethonium cause hyperkalemia?
Suxamethonium can cause hyperkalemia by inducing depolarization, which leads to a significant release of intracellular potassium into the bloodstream.
Why does Suxamethonium cause fasciculation?
Suxamethonium causes fasciculation by acting on distal parts of motor nerve fibers.
Is Suxamethonium contraindicated in burned patients?
Yes, Suxamethonium is contraindicated in patients with burns.
Is Suxamethonium a non-competitive antagonist or agonist?
Suxamethonium is a non-competitive agonist of nicotinic acetylcholine receptors.
What is Suxamethonium chloride used for and how does it work?
Suxamethonium chloride is used in anesthesia to induce muscle relaxation, facilitate endotracheal intubation, and reduce strong muscle contractions.
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