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Suxamethonium

Uses

Suxamethonium is used for skeletal muscle relaxation during surgery.

How it Works

How Suxamethonium works Suxamethonium relaxes the muscles by blocking nerve impulses.

Side Effects

Common side effects of Suxamethonium include rash, increased intraocular pressure, elevated potassium levels in the blood, postoperative muscle pain, slow heart rate, tachycardia, skin flushing, muscle twitching, myoglobinemia, and myoglobinuria.

Expert Advice

  • Suxamethonium is administered as an injection into a vein under the supervision of a doctor.
  • This medication may cause dizziness or drowsiness.
  • Do not drive until you are aware of how Suxamethonium affects you.
  • Your doctor will regularly monitor your blood pressure, as this medication may lead to elevated blood pressure.
  • Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

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Frequently asked questions

Suxamethonium is a short-acting muscle relaxant with a depolarizing effect at the neuromuscular junction that is not pharmacologically reversible.
Yes, Suxamethonium is still utilized during general anesthesia.
Suxamethonium apnoea occurs when a patient lacks the enzymes to metabolize the drug, resulting in prolonged paralysis and inadequate breathing after anesthesia.
Suxamethonium sensitivity refers to a prolonged effect of the drug, resulting in extended muscle relaxation.
At normal therapeutic doses, Suxamethonium does not cross the placental barrier in significant amounts.
Suxamethonium can cause bradycardia due to its initial metabolite stimulating muscarinic receptors in the sinus node, leading to a transient negative chronotropic effect. This can be treated with atropine if it occurs with repeated dosing.
Suxamethonium can cause hyperkalemia by inducing depolarization, which leads to a significant release of intracellular potassium into the bloodstream.
Suxamethonium causes fasciculation by acting on distal parts of motor nerve fibers.
Yes, Suxamethonium is contraindicated in patients with burns.
Suxamethonium is a non-competitive agonist of nicotinic acetylcholine receptors.
Suxamethonium chloride is used in anesthesia to induce muscle relaxation, facilitate endotracheal intubation, and reduce strong muscle contractions.
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