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Sorafenib

Uses

Sorafenib is used in the treatment of liver cancer, kidney cancer, and thyroid cancer.

How it Works

How Sorafenib works Sorafenib is an anti-cancer medication that functions by inhibiting the action of the abnormal protein responsible for signaling cancer cells to multiply. This mechanism helps to halt or slow the proliferation of cancer cells.

Side Effects

Common side effects of Sorafenib include fatigue, nausea, diarrhea, abdominal pain, hair loss, weight loss, anemia (low red blood cell count), infection, high blood pressure, decreased appetite, lymphopenia, hand-foot syndrome, hair follicle inflammation, and hemorrhage.

Expert Advice

  • Sorafenib is indicated for the treatment of liver, kidney, and thyroid cancer.
  • Take it without food or with a low-fat meal, accompanied by a full glass of water.
  • Administer at the same time every day to maintain consistent levels in your body.
  • Women who could become pregnant should use a reliable method of contraception to prevent pregnancy while taking this medication.
  • Your doctor may regularly monitor your blood pressure during treatment with this medication.
  • Inform your doctor if you experience a skin rash or any pain, swelling, or redness in your hands and feet while on this medication.
  • Do not alter the dose or discontinue use without consulting your doctor.

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Frequently asked questions

How is Sorafenib administered?
Sorafenib is an oral medication that should be taken as directed by your doctor. It can be taken with or without food, but avoid high-fat meals as they can reduce its effectiveness. If you have a high-fat meal, take Sorafenib one hour before or two hours after.
Does Sorafenib affect blood sugar levels?
Yes, Sorafenib can lower blood sugar levels significantly, potentially causing fainting. Diabetic patients should monitor their blood sugar regularly and consult their doctor regarding any necessary adjustments to anti-diabetic medication.
For how long do I need to take Sorafenib?
Continue taking Sorafenib for the duration recommended by your doctor, provided it suits you. If you experience bothersome side effects, consult your doctor immediately.
How do I know if I am responding to Sorafenib?
Your doctor will likely recommend regular scans to monitor tumor size and may also conduct blood tests to assess liver and kidney function during your treatment with Sorafenib.
Do I need to take a treatment along with Sorafenib for it to work?
Sorafenib is typically used as a monotherapy, meaning it is administered alone rather than in combination with other treatments like radiotherapy or chemotherapy.
What are the serious side effects that can occur while taking Sorafenib?
Serious side effects may include heart attack, heart failure, increased bleeding risk, high blood pressure, skin issues, and wound healing problems. Other potential concerns identified through tests include decreased blood flow to the heart, liver swelling, gastrointestinal perforation, QT prolongation, and thyroid hormone level changes.
I have developed redness and pain in my palms and soles ever since I started using Sorafenib. My skin is also coming off. Is this dangerous? What should I do?
You may be experiencing a hand and foot skin reaction due to Sorafenib. Consult your doctor, who may adjust your therapy, change your dosage, or recommend topical treatments. If the condition is severe, seek advice from a dermatologist.
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