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Simvastatin

Uses

Simvastatin is used in the treatment of high cholesterol, high triglycerides, and the prevention of heart attacks and strokes.

How it Works

How Simvastatin works Simvastatin is a lipid-lowering medication classified as a statin. It functions by inhibiting an enzyme known as HMG-CoA reductase, which is essential for the body to produce cholesterol. This action reduces "bad" cholesterol (LDL) and triglycerides while increasing the level of "good" cholesterol (HDL).

Side Effects

Common side effects of Simvastatin include constipation, headache, upper respiratory tract infection, abdominal pain, and nausea.

Expert Advice

Simvastatin should be taken in the evening after dinner and before sleeping.
It should be used in conjunction with regular exercise and a low-fat diet to lower blood fat levels.
Inform your doctor if you experience:

Fatigue
Muscle weakness
Muscle pain

Your doctor may check your liver function before starting treatment and regularly thereafter.
Notify your doctor if you notice signs of liver problems, including:

Stomach pains
Unusually dark urine
Yellowing of the skin or eyes

Inform your doctor if you have:

Kidney disease
Liver disease
Diabetes

If you are diabetic, monitor your blood sugar levels regularly, as Simvastatin may cause an increase in blood sugar levels.
Do not take Simvastatin if you are:

Pregnant
Planning a pregnancy
Breastfeeding

Simvastatin treats high cholesterol by lowering "bad" cholesterol (LDL) and triglycerides (fats).
It also reduces the risk of heart attack and stroke.
In general, Simvastatin is considered safe, but it may cause:

Diarrhea
Gas
Upset stomach

If you experience any of these side effects, take the medication with food.

Other Combinations

Ezetimibe + Simvastatin

Aspirin + Atenolol + Hydrochlorothiazide + Ramipril + Simvastatin

Related Medications

Salt Composition in both

Simvastatin 10mg

SIN 10mg Tablet

East West Pharma

Strip of 10 tablets

₹54.7

Simvofix 10mg Tablet 10s

Bal Pharma Ltd.

Strip of 10 tablets

₹68

MRP ₹83

Salt Composition in both

Simvastatin 10mg

Simvotin 10mg Tablet 10s

Sun Pharmaceutical Industries Ltd.

Strip of 10 tablets

₹193.1

Simvofix 10mg Tablet 10s

Bal Pharma Ltd.

Strip of 10 tablets

₹68

MRP ₹83

Salt Composition in both

Simvastatin 10mg

Simaid 10mg Tablet

Maiden Pharmaceutical Ltd.

Strip of 10 tablets

₹78.4

Simvofix 10mg Tablet 10s

Bal Pharma Ltd.

Strip of 10 tablets

₹68

MRP ₹83

Salt Composition in both

Simvastatin 10mg

Simlo 10mg Tablet

Ipca Laboratories Ltd.

Strip of 10 tablets

₹97

Simvofix 10mg Tablet 10s

Bal Pharma Ltd.

Strip of 10 tablets

₹68

MRP ₹83

Salt Composition in both

Simvastatin 10mg

Zosta 10 Tablet

Strip of 10 tablets

₹107.2

Simvofix 10mg Tablet 10s

Bal Pharma Ltd.

Strip of 10 tablets

₹68

MRP ₹83

Salt Composition in both

Simvastatin 20mg

Vastatin 20mg Tablet

Aurobindo Pharma Ltd.

Strip of 10 tablets

₹125

Simvotin 20mg Tablet 10s

Sun Pharmaceutical Industries Ltd.

Strip of 10 tablets

₹260.6

MRP ₹317.8

Salt Composition in both

Simvastatin 20mg

Simvin 20mg Tablet

Medley Pharmaceuticals

Strip of 10 tablets

₹78

Simvotin 20mg Tablet 10s

Sun Pharmaceutical Industries Ltd.

Strip of 10 tablets

₹260.6

MRP ₹317.8

Salt Composition in both

Simvastatin 10mg

Svt Film 10mg Tablet

Elder Pharmaceuticals Ltd.

Strip of 10 tablets

₹61.6

Simvofix 10mg Tablet 10s

Bal Pharma Ltd.

Strip of 10 tablets

₹68

MRP ₹83

Salt Composition in both

Simvastatin 20mg

Simvastol 20mg Tablet 10 tablets

Themis Medicare Ltd.

Strip of 10 tablets

₹75

Simvotin 20mg Tablet 10s

Sun Pharmaceutical Industries Ltd.

Strip of 10 tablets

₹260.6

MRP ₹317.8

Salt Composition in both

Simvastatin 20mg

Sim Hdl 20mg Tablet 10s

Dr. Morepen Ltd.

Strip of 10 tablets

₹276

Simvotin 20mg Tablet 10s

Sun Pharmaceutical Industries Ltd.

Strip of 10 tablets

₹260.6

MRP ₹317.8

Salt Composition in both

Simvastatin 20mg

Simvastat 20mg Tablet 10s

Prevego Healthcare & Research Pvt. Ltd.

Strip of 10 tablets

₹284

Simvotin 20mg Tablet 10s

Sun Pharmaceutical Industries Ltd.

Strip of 10 tablets

₹260.6

MRP ₹317.8

Salt Composition in both

Simvastatin 20mg

Simvofix 20mg Tablet

Bal Pharma Ltd.

Strip of 10 tablets

₹82.9

Simvotin 20mg Tablet 10s

Sun Pharmaceutical Industries Ltd.

Strip of 10 tablets

₹260.6

MRP ₹317.8

Salt Composition in both

Simvastatin 20mg

SIN 20mg Tablet

East West Pharma

Strip of 10 tablets

₹94.5

Simvotin 20mg Tablet 10s

Sun Pharmaceutical Industries Ltd.

Strip of 10 tablets

₹260.6

MRP ₹317.8

Salt Composition in both

Simvastatin 20mg

Simvastol 20mg Tablet 25 tablets

Themis Medicare Ltd.

Strip of 25 tablets

₹75.7

Simvotin 20mg Tablet 10s

Sun Pharmaceutical Industries Ltd.

Strip of 10 tablets

₹260.6

MRP ₹317.8

Salt Composition in both

Simvastatin 20mg

Corstat 20mg Tablet

Medreich Lifecare Ltd.

Strip of 14 tablets

₹110

Simvotin 20mg Tablet 10s

Sun Pharmaceutical Industries Ltd.

Strip of 10 tablets

₹260.6

MRP ₹317.8

Salt Composition in both

Simvastatin 20mg

Biosim 20mg Tablet

Biochem Pharmaceutical Industries

Strip of 10 tablets

₹68.2

Simvotin 20mg Tablet 10s

Sun Pharmaceutical Industries Ltd.

Strip of 10 tablets

₹260.6

MRP ₹317.8

Salt Composition in both

Simvastatin 20mg

Simoz 20mg Tablet

Klintoz Pharmaceuticals Pvt. Ltd.

Strip of 10 tablets

₹100

Simvotin 20mg Tablet 10s

Sun Pharmaceutical Industries Ltd.

Strip of 10 tablets

₹260.6

MRP ₹317.8

Salt Composition in both

Simvastatin 20mg

Simlup 20mg Tablet

Strip of 10 tablets

₹52.5

Simvotin 20mg Tablet 10s

Sun Pharmaceutical Industries Ltd.

Strip of 10 tablets

₹260.6

MRP ₹317.8

Salt Composition in both

Simvastatin 20mg

S Vastin 20mg Tablet

Neocardiab care

Strip of 10 tablets

₹89

Simvotin 20mg Tablet 10s

Sun Pharmaceutical Industries Ltd.

Strip of 10 tablets

₹260.6

MRP ₹317.8

Salt Composition

Simvastatin 40mg

SIM HDL 40 Tablet 10s

Dr. Morepen Ltd.

Strip of 10 tablets

₹331

Sorry, the substitute medicine is Currently Unavailable

Salt Composition

Simvastatin 5mg

Simtron 5mg Tablet 10s

Chemo Healthcare Pvt. Ltd.

Strip of 10 tablets

₹24.4

Sorry, the substitute medicine is Currently Unavailable

Salt Composition

Simvastatin 5mg

Sqtine 5mg Tablet

Cubit Healthcare

Strip of 10 tablets

₹56.5

Sorry, the substitute medicine is Currently Unavailable

Salt Composition

Simvastatin 5mg

Zosta 5mg Tablet

Strip of 10 tablets

₹62.1

Sorry, the substitute medicine is Currently Unavailable

Salt Composition

Simvastatin 5mg

Simlo 5mg Tablet

Ipca Laboratories Ltd.

Strip of 10 tablets

₹53

Sorry, the substitute medicine is Currently Unavailable

Salt Composition

Simvastatin 40mg

Simvotin 40 Tablet

Sun Pharmaceutical Industries Ltd.

Strip of 10 tablets

₹300

Sorry, the substitute medicine is Currently Unavailable

Frequently asked questions

Is Simvastatin safe for use?

Yes, Simvastatin is considered safe when used as prescribed, and side effects are generally minimal and not experienced by everyone.

Can Simvastatin cause fatigue?

Yes, Simvastatin can lead to fatigue due to reduced energy supply to muscles, though the exact cause is unclear. Fatigue may be more pronounced in individuals with heart disease or liver issues. Consult your doctor if you experience significant tiredness while on this medication.

What is high cholesterol and its effects?

Cholesterol is a type of fat in your blood, comprising LDL ('bad') and HDL ('good') cholesterol. High LDL levels can lead to plaque buildup in blood vessels, increasing the risk of heart disease and stroke, while HDL helps prevent this buildup. Elevated triglycerides are also harmful.

When is the best time to take Simvastatin?

Simvastatin is typically taken once daily in the evening after dinner. Consistency in timing helps with adherence to the medication regimen.

What is the duration of Simvastatin treatment?

Simvastatin may need to be taken indefinitely or as directed by your doctor. Discontinuing it without an alternative treatment can lead to increased cholesterol levels. It is generally safe with minimal side effects when taken as prescribed.

What is the purpose and mechanism of Simvastatin?

Simvastatin is a statin medication that lowers blood cholesterol. It is used in conjunction with a healthy diet and exercise to reduce LDL and increase HDL cholesterol. It works by inhibiting cholesterol production in the liver, thereby lowering arterial cholesterol levels and reducing heart attack and stroke risk.

Is it safe to consume alcohol while taking Simvastatin?

No, alcohol should be avoided while taking Simvastatin, as it increases the risk of liver problems and can elevate triglyceride levels, potentially leading to liver damage and exacerbating side effects like muscle pain. Those with liver issues should consult their doctor before use.

Which foods should be avoided while taking Simvastatin?

To enhance the effectiveness of Simvastatin, avoid high-calorie foods like fried and junk food. A low-fat, low-cholesterol diet is recommended, along with adherence to your doctor's dietary and exercise advice.

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