Simvastatin

Uses

Simvastatin is used in the treatment of high cholesterol, high triglycerides, and the prevention of heart attacks and strokes.

How it Works

How Simvastatin works Simvastatin is a lipid-lowering medication classified as a statin. It functions by inhibiting an enzyme known as HMG-CoA reductase, which is essential for the body to produce cholesterol. This action reduces "bad" cholesterol (LDL) and triglycerides while increasing the level of "good" cholesterol (HDL).

Side Effects

Common side effects of Simvastatin include constipation, headache, upper respiratory tract infection, abdominal pain, and nausea.

Expert Advice

Simvastatin should be taken in the evening after dinner and before sleeping.
It should be used in conjunction with regular exercise and a low-fat diet to lower blood fat levels.
Inform your doctor if you experience:

Fatigue
Muscle weakness
Muscle pain

Your doctor may check your liver function before starting treatment and regularly thereafter.
Notify your doctor if you notice signs of liver problems, including:

Stomach pains
Unusually dark urine
Yellowing of the skin or eyes

Inform your doctor if you have:

Kidney disease
Liver disease
Diabetes

If you are diabetic, monitor your blood sugar levels regularly, as Simvastatin may cause an increase in blood sugar levels.
Do not take Simvastatin if you are:

Pregnant
Planning a pregnancy
Breastfeeding

Simvastatin treats high cholesterol by lowering "bad" cholesterol (LDL) and triglycerides (fats).
It also reduces the risk of heart attack and stroke.
In general, Simvastatin is considered safe, but it may cause:

Diarrhea
Gas
Upset stomach

If you experience any of these side effects, take the medication with food.

Other Combinations

Ezetimibe + Simvastatin

Aspirin + Atenolol + Hydrochlorothiazide + Ramipril + Simvastatin

Related Medications

Salt Composition in both

Simvastatin 10mg

G Sim 10mg Tablet

GR Healthcare Laboratories

Strip of 10 tablets

₹79

Simcardia 10mg Tablet 10s

Healing Pharma India Pvt. Ltd.

Strip of 10 tablets

₹92.5

MRP ₹185

Salt Composition in both

Simvastatin 10mg

Zocor 10mg Tablet 15s

MSD Pharmaceuticals Pvt. Ltd.

Strip of 15 tablets

₹180

Simcardia 10mg Tablet 10s

Healing Pharma India Pvt. Ltd.

Strip of 10 tablets

₹92.5

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Salt Composition in both

Simvastatin 10mg

Simoz 10mg Tablet

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Strip of 10 tablets

₹74

Simcardia 10mg Tablet 10s

Healing Pharma India Pvt. Ltd.

Strip of 10 tablets

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MRP ₹185

Salt Composition in both

Simvastatin 10mg

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Strip of 10 tablets

₹26.5

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Salt Composition in both

Simvastatin 10mg

Alvastin 10mg Tablet 10s

Allied Chemicals & Pharmaceuticals Pvt. Ltd.

Strip of 10 tablets

₹70

Simcardia 10mg Tablet 10s

Healing Pharma India Pvt. Ltd.

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₹92.5

MRP ₹185

Salt Composition in both

Simvastatin 10mg

Simvatic 10 Tablet

Johnlee Pharmaceuticals Pvt. Ltd.

Strip of 10 tablets

₹120

Simcardia 10mg Tablet 10s

Healing Pharma India Pvt. Ltd.

Strip of 10 tablets

₹92.5

MRP ₹185

Salt Composition in both

Simvastatin 10mg

Simvas 10mg Tablet 10 tablets

Micro Labs Ltd.

Strip of 10 tablets

₹41

Simcardia 10mg Tablet 10s

Healing Pharma India Pvt. Ltd.

Strip of 10 tablets

₹92.5

MRP ₹185

Salt Composition in both

Simvastatin 10mg

Biosim 10mg Tablet

Biochem Pharmaceutical Industries

Strip of 10 tablets

₹36

Simcardia 10mg Tablet 10s

Healing Pharma India Pvt. Ltd.

Strip of 10 tablets

₹92.5

MRP ₹185

Salt Composition in both

Simvastatin 10mg

Gatosim 10mg Tablet

Cmg Biotech Pvt. Ltd.

Strip of 10 tablets

₹69

Simcardia 10mg Tablet 10s

Healing Pharma India Pvt. Ltd.

Strip of 10 tablets

₹92.5

MRP ₹185

Salt Composition in both

Simvastatin 10mg

Simvas 10mg Tablet 15 tablets

Micro Labs Ltd.

Strip of 15 tablets

₹74.9

Simcardia 10mg Tablet 10s

Healing Pharma India Pvt. Ltd.

Strip of 10 tablets

₹92.5

MRP ₹185

Salt Composition in both

Simvastatin 10mg

Simtil 10mg Tablet

Tablets India Ltd.

Strip of 10 tablets

₹51.3

Simcardia 10mg Tablet 10s

Healing Pharma India Pvt. Ltd.

Strip of 10 tablets

₹92.5

MRP ₹185

Salt Composition in both

Simvastatin 10mg

Simdia 10mg Tablet

Zee Laboratories

Strip of 10 tablets

₹96

Simcardia 10mg Tablet 10s

Healing Pharma India Pvt. Ltd.

Strip of 10 tablets

₹92.5

MRP ₹185

Salt Composition in both

Simvastatin 10mg

Vastocor 10mg Tablet

Strip of 10 tablets

₹120

Simcardia 10mg Tablet 10s

Healing Pharma India Pvt. Ltd.

Strip of 10 tablets

₹92.5

MRP ₹185

Salt Composition in both

Simvastatin 20mg

Eurosim 20mg Tablet

Strip of 10 tablets

₹160

Simtron 20mg Tablet 10s

Chemo Healthcare Pvt. Ltd.

Strip of 10 tablets

₹94.5

MRP ₹189

Salt Composition in both

Simvastatin 20mg

Gatosim 20mg Tablet

Cmg Biotech Pvt. Ltd.

Strip of 10 tablets

₹50

Simtron 20mg Tablet 10s

Chemo Healthcare Pvt. Ltd.

Strip of 10 tablets

₹94.5

MRP ₹189

Salt Composition in both

Simvastatin 20mg

Simastin 20mg Tablet

Alkem Laboratories Ltd.

Strip of 10 tablets

₹30

Simtron 20mg Tablet 10s

Chemo Healthcare Pvt. Ltd.

Strip of 10 tablets

₹94.5

MRP ₹189

Salt Composition in both

Simvastatin 20mg

Simlip 20mg Tablet

Strip of 10 tablets

₹31.3

Simtron 20mg Tablet 10s

Chemo Healthcare Pvt. Ltd.

Strip of 10 tablets

₹94.5

MRP ₹189

Salt Composition in both

Simvastatin 20mg

Simwel 20 Tablet

Wel N Innov Pharmaceuticals

Strip of 10 tablets

₹220

Simtron 20mg Tablet 10s

Chemo Healthcare Pvt. Ltd.

Strip of 10 tablets

₹94.5

MRP ₹189

Salt Composition in both

Simvastatin 20mg

Simkind 20mg Tablet

Innovative Pharmaceuticals

Strip of 10 tablets

₹145

Simtron 20mg Tablet 10s

Chemo Healthcare Pvt. Ltd.

Strip of 10 tablets

₹94.5

MRP ₹189

Salt Composition in both

Simvastatin 20mg

Zocor 20mg Tablet 10s

MSD Pharmaceuticals Pvt. Ltd.

Strip of 10 tablets

₹172.6

Simtron 20mg Tablet 10s

Chemo Healthcare Pvt. Ltd.

Strip of 10 tablets

₹94.5

MRP ₹189

Salt Composition

Simvastatin 5mg

Svt Film 5mg Tablet

Elder Pharmaceuticals Ltd.

Strip of 10 tablets

₹36

Sorry, the substitute medicine is Currently Unavailable

Salt Composition

Simvastatin 5mg

Simvastol 5mg Tablet

Themis Medicare Ltd.

Strip of 25 tablets

₹25

Sorry, the substitute medicine is Currently Unavailable

Salt Composition

Simvastatin 5mg

Simoz 5mg Tablet

Klintoz Pharmaceuticals Pvt. Ltd.

Strip of 10 tablets

₹49

Sorry, the substitute medicine is Currently Unavailable

Salt Composition

Simvastatin 5mg

Simchol 5mg Tablet

Aristo Pharmaceuticals Pvt. Ltd.

Strip of 10 tablets

₹36.6

Sorry, the substitute medicine is Currently Unavailable

Salt Composition

Simvastatin 5mg

Simvotin 5 Tablet

Sun Pharmaceutical Industries Ltd.

Strip of 10 tablets

₹78

Sorry, the substitute medicine is Currently Unavailable

Frequently asked questions

Is Simvastatin safe for use?

Yes, Simvastatin is considered safe when used as prescribed, and side effects are generally minimal and not experienced by everyone.

Can Simvastatin cause fatigue?

Yes, Simvastatin can lead to fatigue due to reduced energy supply to muscles, though the exact cause is unclear. Fatigue may be more pronounced in individuals with heart disease or liver issues. Consult your doctor if you experience significant tiredness while on this medication.

What is high cholesterol and its effects?

Cholesterol is a type of fat in your blood, comprising LDL ('bad') and HDL ('good') cholesterol. High LDL levels can lead to plaque buildup in blood vessels, increasing the risk of heart disease and stroke, while HDL helps prevent this buildup. Elevated triglycerides are also harmful.

When is the best time to take Simvastatin?

Simvastatin is typically taken once daily in the evening after dinner. Consistency in timing helps with adherence to the medication regimen.

What is the duration of Simvastatin treatment?

Simvastatin may need to be taken indefinitely or as directed by your doctor. Discontinuing it without an alternative treatment can lead to increased cholesterol levels. It is generally safe with minimal side effects when taken as prescribed.

What is the purpose and mechanism of Simvastatin?

Simvastatin is a statin medication that lowers blood cholesterol. It is used in conjunction with a healthy diet and exercise to reduce LDL and increase HDL cholesterol. It works by inhibiting cholesterol production in the liver, thereby lowering arterial cholesterol levels and reducing heart attack and stroke risk.

Is it safe to consume alcohol while taking Simvastatin?

No, alcohol should be avoided while taking Simvastatin, as it increases the risk of liver problems and can elevate triglyceride levels, potentially leading to liver damage and exacerbating side effects like muscle pain. Those with liver issues should consult their doctor before use.

Which foods should be avoided while taking Simvastatin?

To enhance the effectiveness of Simvastatin, avoid high-calorie foods like fried and junk food. A low-fat, low-cholesterol diet is recommended, along with adherence to your doctor's dietary and exercise advice.

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