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Selegiline

Uses

Selegiline is used in the treatment of Parkinson's disease.

How it Works

Selegiline works by increasing the amount of dopamine, a chemical messenger essential for controlling movement in the brain.

Side Effects

Common side effects of Selegiline include joint pain, insomnia (difficulty sleeping), vomiting, dizziness, constipation, diarrhea, confusion, hallucinations, movement disorders, headache, vertigo, hypotension (low blood pressure), slow heart rate, muscle cramps, fatigue, breathlessness, rash, pharyngitis, sinus inflammation, mouth ulcers, and increased liver enzymes.

Expert Advice

  • You have been prescribed Selegiline to treat your symptoms of Parkinson's disease.
  • It should preferably be taken with breakfast or lunch, as taking it late in the day may cause trouble sleeping.
  • It can make you dizzy or lightheaded, especially when you suddenly stand up from sitting or lying down. Therefore, get out of bed slowly, resting your feet on the floor for a few minutes before standing up.
  • Avoid eating foods high in tyramine (e.g., aged cheeses, air-dried meats, soy sauce, tap/draft beers, and red wines) while taking Selegiline, as this can cause an unsafe rise in your blood pressure.
  • Do not stop taking Selegiline suddenly without consulting your doctor, as this can be dangerous.
  • Parkinson's disease can increase your risk for skin cancer. Talk to your doctor if you notice any unusual growths or bumps on your skin.
  • Inform your doctor if you are also taking medications for depression or mood disorders.

Other Combinations

Frequently asked questions

Is Selegiline safe?
Selegiline is safe when used at the prescribed doses and duration recommended by your doctor.
Is Selegiline addictive?
Selegiline is not considered addictive.
Is Selegiline a stimulant?
Selegiline can stimulate the brain, potentially leading to mood changes, anxiety, agitation, hallucinations, confusion, and sleep disturbances.
Is Selegiline neuroprotective?
Selegiline has neuroprotective properties and may slow the progression of Parkinson's disease.
Is Selegiline a dopamine agonist?
Selegiline is not a dopamine agonist; it enhances dopamine activity in the brain by inhibiting its breakdown.
Does Selegiline need to be tapered?
Selegiline should be tapered off rather than stopped abruptly to avoid symptoms like fever, sweating, muscle stiffness, and loss of consciousness.
Does Selegiline cause weight loss or gain?
Selegiline is associated with weight loss.
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