Rofecoxib and Tizanidine are used for pain relief.
How Rofecoxib and Tizanidine work Rofecoxib and Tizanidine is a combination of two medicines: Rofecoxib and Tizanidine, which relieve pain and relax the muscles. Rofecoxib is a non-steroidal anti-inflammatory drug (NSAID) that works by blocking the release of certain chemical messengers that cause pain and inflammation, including redness and swelling. Tizanidine is a muscle relaxant that acts on the centers in the brain and spinal cord to alleviate muscle stiffness or spasms and to improve pain and muscle movement.
Common side effects of Rofecoxib and Tizanidine include diarrhea, stomach pain, indigestion, dryness in the mouth, flatulence, swelling of the hands, swelling of the feet, weakness, sleepiness, dizziness, and flu-like symptoms.