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Pyrimethamine + Sulfamethoxazole

Uses

Pyrimethamine and Sulfamethoxazole are used in the treatment of malaria.

How it Works

How Pyrimethamine and Sulfamethoxazole work Pyrimethamine and Sulfamethoxazole is a combination of two medicines that treat malaria. Pyrimethamine is an antiparasitic medication that works by increasing the levels of heme in the blood, a substance toxic to the malarial parasite. This action kills the parasite and prevents the infection from spreading. Sulfamethoxazole is an antibiotic that inhibits bacteria from producing folic acid, a nutrient necessary for bacterial multiplication.

Side Effects

Common side effects of Pyrimethamine and Sulfamethoxazole include diarrhea, nausea, vomiting, fatigue, a feeling of fullness, dizziness, headache, mouth sores, and skin rash.

Expert Advice

  • Pyrimethamine + Sulfamethoxazole must be taken with food at the same time every day.
  • Do not skip any doses and complete the full course of treatment, even if you feel better.
  • Stopping the medication early may cause the infection to return and make it harder to treat.
  • It is advisable to drink plenty of fluids and maintain a healthy diet while taking the medication.
  • This medication may cause dizziness; avoid driving or engaging in activities that require mental focus until you know how it affects you.
  • Avoid consuming alcohol while on this medication, as it may increase the risk of side effects.
  • Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

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Frequently asked questions

What should I do if I miss a dose of Pyrimethamine+Sulfamethoxazole?
Take the missed dose as soon as you remember, but skip it if it's almost time for your next dose. Do not take an extra dose to compensate for the missed one.
Is it okay to stop Pyrimethamine+Sulfamethoxazole once I feel better?
No, you must complete the entire course of Pyrimethamine+Sulfamethoxazole, even if you feel better, as symptoms may improve before the infection is fully resolved.
What should I do if I don't improve after taking Pyrimethamine+Sulfamethoxazole?
Notify your doctor if you do not feel better after completing the full treatment course, or if your symptoms worsen during the medication.
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