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Protamine sulfate

Uses

Protamine sulfate is used in the treatment of heparin overdose.

How it Works

How Protamine sulfate works Protamine sulfate is utilized to counteract the anticoagulant effects of heparin and to stop bleeding in patients caused by heparin.

Expert Advice

  • Inform your doctor if you have undergone heart surgery.
  • Notify your doctor if you have diabetes and have received protamine insulin.
  • Disclose any allergies to fish.
  • Inform your doctor if you have had a vasectomy or are infertile and may have antibodies to protamine, as you may be at an increased risk of experiencing an allergic reaction to protamine.
  • You will be monitored to confirm whether your blood clotting parameters are within normal limits if you are receiving multiple doses or prolonged administration of protamine.
  • You may experience a sudden drop in blood pressure, breathlessness, or chest and abdominal pain when receiving protamine.
  • Inform your doctor if you are pregnant, think you may become pregnant, or are breastfeeding.
  • Do not take protamine if you are allergic to protamine sulfate or any of its ingredients.

Other Combinations

Frequently asked questions

Protamine has anticoagulant effects when administered alone, but it neutralizes heparin, losing its anticoagulant activity in that context.
Yes, protamine sulphate is used as an antidote for Lovenox overdose.
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