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Probenecid

Uses

Probenecid is used in the treatment of gout.

How it Works

How Probenecid Works Probenecid is a urine alkalizer. It functions by increasing the pH of urine, making it less acidic. This process aids the kidneys in eliminating excess uric acid, thereby preventing gout and certain types of kidney stones.

Side Effects

Common side effects of Probenecid include nausea, vomiting, headache, gout flares, fever, rash, aplastic anemia, hemolytic anemia, and decreased white blood cell count (lymphocytes).

Expert Advice

  • Do not use probenecid along with salicylates, such as aspirin.
  • You may be prescribed colchicine or a non-steroidal anti-inflammatory agent (NSAID, pain killer) to prevent severe gouty attacks during the first 6 to 12 months of probenecid therapy.
  • Consult your doctor before starting probenecid treatment if you have or have ever had:
    • Kidney stones
    • Any other kidney disorder
    • Ulcers in the stomach and small intestine (peptic ulcers)
    • Diabetes
    • Severe liver disorders
    • Blood disorders
    • Glucose 6-phosphate dehydrogenase (G6PD) deficiency
  • Inform your doctor about any scheduled surgery for which you will be receiving anesthetics.
  • You should consume adequate water or fluids while taking probenecid to prevent kidney stones.
  • Notify your doctor if you are pregnant, planning to become pregnant, or are breastfeeding.
  • Take precautions while driving or operating machinery, as probenecid is known to cause dizziness.

Other Combinations

Amoxycillin + Cloxacillin + Probenecid

Amoxycillin + Probenecid

Ampicillin + Probenecid

Cefadroxil + Probenecid

Cefalexin + Probenecid

Related Medications

Molecule
Salt Composition

Probenecid 500mg

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Bencid 500mg Tablet 10s
Geno Pharmaceuticals Ltd.
Strip of 10 tablets
MRP

₹70.1

No Substitute
Sorry, Substitute Medicine is Unavailable
Molecule
Salt Composition

Ampicillin 750mg + Probenecid

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Apc Tablet
Algen Healthcare Ltd.
Strip of 10 tablets
MRP

₹89

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Molecule
Salt Composition

Amoxicillin 500mg + Probenecid 500mg

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Moxylong DS 500 mg/500 mg Tablet
Dr. Reddy's Laboratories Ltd.
Strip of 10 tablets
MRP

₹75.4

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Molecule
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Ampicillin 500mg + Probenecid 500mg

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Ampilong DS 500/500mg Tablet 10s
Dr. Reddy's Laboratories Ltd.
Strip of 10 tablets
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₹71.8

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Molecule
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Cefadroxil 500mg + Probenecid 500mg

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Nocid OM 500mg/500mg Capsule
Rubra Pharmaceuticals Ltd.
Strip of 10 capsules

MRP ₹42.2

Molecule
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Cefalexin 250mg + Probenecid 250mg

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Phexibid 250mg/250mg Tablet
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Strip of 10 tablets
MRP

₹60.9

No Substitute
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Molecule
Salt Composition

Cefalexin 500mg + Probenecid 500mg

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Phexibid Forte 500mg/500mg Tablet
Cyper Drugs & Pharmaceuticals Pvt. Ltd.
Strip of 10 tablets
MRP

₹103.1

No Substitute
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Molecule
Salt Composition

Cefalexin NA + Probenecid NA

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Procef Forte Tablet
Alpha Pharmaceuticals
Strip of 10 tablets

MRP ₹148.5

Molecule
Salt Composition

Cefadroxil 500mg + Probenecid 500mg

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Mydrox 500mg/500mg Tablet
Solitaire Pharmacia Pvt. Ltd.
Strip of 10 tablets

MRP ₹43.6

Molecule
Salt Composition

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Mydrox 250mg/250mg Tablet
Solitaire Pharmacia Pvt. Ltd.
Strip of 10 tablets

MRP ₹22.5

Molecule
Salt Composition

Cefadroxil 500mg + Probenecid 500mg

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Dax LA 500 mg/500 mg Tablet
DWD Pharmaceuticals Ltd.
Strip of 6 tablets

MRP ₹25.1

Molecule
Salt Composition

Cefalexin 500mg + Probenecid 500mg

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Alcephin LA 500/500mg Tablet 10s
Alembic Pharmaceuticals Ltd.
Strip of 10 tablets
MRP

₹112.7

No Substitute
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Molecule
Salt Composition

Cefalexin 500mg + Probenecid 250mg

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Unifex Forte 500mg/250mg Tablet
BestoChem Formulations India Ltd.
Strip of 10 tablets
MRP

₹201.6

No Substitute
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Molecule
Salt Composition

Ampicillin 250mg + Probenecid 250mg

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Prompicin 250/250mg Capsule 10s
Geno Pharmaceuticals Ltd.
Strip of 10 capsules
MRP

₹34.5

No Substitute
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Molecule
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Ampicillin NA + Probenecid NA

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Longact Tablet
Mech Pharmaceuticals
Strip of 10 tablets
MRP

₹50.3

No Substitute
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Molecule
Salt Composition

Cefadroxil NA + Probenecid NA

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Distaclor PD Drop 10ml
Pharma Link Pvt. Ltd.
Packet of 10 ml
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₹86.3

No Substitute
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Molecule
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Cefalexin 250mg + Probenecid 250mg

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Ceff LA 250/250mg Tablet 10s
Lupin Ltd.
Strip of 10 tablets
MRP

₹86.3

No Substitute
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Molecule
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Cefalexin 500mg + Probenecid 500mg

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Cefalong DS 500mg/500mg Capsule
Dr. Reddy's Laboratories Ltd.
Strip of 10 capsules
MRP

₹125.8

No Substitute
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Molecule
Salt Composition

Amoxicillin 250mg + Probenecid 250mg

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Moxylong SS 250 mg/250 mg Tablet
Dr. Reddy's Laboratories Ltd.
Strip of 10 tablets
MRP

₹40.3

No Substitute
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Molecule
Salt Composition

Ampicillin 250mg + Probenecid 250mg

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Ampilong 250/250mg Tablet 10s
Dr. Reddy's Laboratories Ltd.
Strip of 10 tablets
MRP

₹37.2

No Substitute
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Molecule
Salt Composition

Cefadroxil 250mg + Probenecid 250mg

hero_image
Dax LA 250 mg/250 mg Tablet
DWD Pharmaceuticals Ltd.
Strip of 6 tablets

MRP ₹13

Molecule
Salt Composition

Cefalexin 500mg + Probenecid 500mg

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Ceff LA 500/500mg Tablet 10s
Lupin Ltd.
Strip of 10 tablets
MRP

₹174

No Substitute
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Molecule
Salt Composition

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Procef Forte 500mg/500mg Tablet
Alpha Drugs & Pharmaceuticals
Strip of 10 tablets
MRP

₹112.5

No Substitute
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Molecule
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Alcephin LA 250/250mg Tablet 10s
Alembic Pharmaceuticals Ltd.
Strip of 10 tablets
MRP

₹66.7

No Substitute
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Molecule
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Cefalexin 250mg + Probenecid 250mg

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Unifex 250 mg/250 mg Tablet
BestoChem Formulations India Ltd.
Strip of 10 tablets
MRP

₹71.4

No Substitute
Sorry, Substitute Medicine is Unavailable

Frequently asked questions

Probenecid is a uricosuric agent used to lower uric acid levels and to prevent and treat gout and gouty arthritis. It is also used to enhance the effectiveness of antibiotics like penicillin.
Yes, kidney stones are a known side effect of probenecid treatment.
Probenecid is prescribed with penicillin in certain serious infections to prolong the antibiotic's effect. It works by inhibiting the kidney's elimination of penicillin, increasing its concentration in the blood.
No, probenecid is a uricosuric agent used to lower uric acid levels and treat gout. It does not have anti-inflammatory properties like NSAIDs, nor does it fight infections like antibiotics or sulfa drugs. It is sometimes used with antibiotics to enhance their effect but is not a diuretic.