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Pizotifen

Uses

Pizotifen is used to prevent migraines.

How it Works

How Pizotifen works Migraine headaches are believed to result from the dilation of blood vessels in the head. Pizotifen is a serotonin antagonist. It works by regulating the level of serotonin, a chemical messenger, in the brain and also prevents the loss of tone and dilation of blood vessels, thereby preventing migraine headaches.

Side Effects

Common side effects of Pizotifen include dryness in the mouth, increased appetite, dizziness, drowsiness, fatigue, nausea, and an increase in body weight.

Expert Advice

  • You have been prescribed Pizotifen for the prevention of migraine headaches. Do not take it to treat an acute attack of migraine.
  • Some tips that may help avoid a migraine attack:
    • Have your meals at the same time every day.
    • Avoid bright lights and extreme temperatures.
    • Avoid loud music and noisy places.
    • Avoid chocolates, cheese, processed food, alcohol, and smoking.
    • Get sufficient sleep and avoid stress.
  • Pizotifen should be taken at night-time before going to bed. It may cause sleepiness.
  • Do not drive or engage in activities that require mental focus until you know how Pizotifen affects you.
  • You may experience weight gain while on treatment; regular monitoring of body weight is required.
  • Notify your doctor if you develop any of the following symptoms:
    • Skin rash
    • Muscle aches
    • Tremors
    • Difficulty moving
    • Abnormal uncontrolled movements

Other Combinations

Related Medications

Frequently asked questions

Yes, Pizotifen may cause dry mouth due to its mild anti-cholinergic side effects.
Yes, Pizotifen can cause sleepiness, drowsiness, and dizziness. It is advisable to avoid driving or operating heavy machinery while taking this medication.
Yes, Pizotifen can cause weight gain due to increased appetite. To manage this, consider incorporating fresh, low-calorie foods into your diet, which are healthier than processed high-calorie options. Consult your doctor for dietary advice, especially since certain foods may trigger migraines.
No, Pizotifen typically does not affect blood pressure. However, exceeding the recommended dose may lead to low blood pressure.
Pizotifen should be taken as prescribed by your doctor. It is intended to prevent migraines rather than treat them, so continue taking it regularly even if you feel well.
Yes, Pizotifen can be safely taken with paracetamol or ibuprofen, as they do not interfere with each other's effects. However, consult your doctor before combining any medications.
Inform your doctor about any medications you are taking, and disclose if you have glaucoma, urinary difficulties, a history of seizures, or kidney issues. Additionally, let your doctor know if you are pregnant, trying to conceive, breastfeeding, or have any intolerance to sugars, as Pizotifen contains lactose.
Taking more than the recommended dose of Pizotifen may result in symptoms such as drowsiness, dizziness, confusion, seizures (especially in children), difficulty breathing, rapid heartbeat, low blood pressure, dry mouth, nausea, bluish skin, coma, or respiratory paralysis. Seek immediate medical assistance if this occurs.
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