Pilocarpine

Uses

Pilocarpine is used in the treatment of dry mouth following radiotherapy for head and neck cancer.

How it Works

How Pilocarpine works Pilocarpine is a cholinergic agonist. It functions by stimulating specific nerves and glands in the body, which increases the production of saliva, tears, sweat, digestive juices, and other secretions.

Side Effects

Common side effects of Pilocarpine include headache, dizziness, blurred vision, diarrhea, stinging in the eyes, superficial keratitis, burning eyes, eye itching, eye redness, and increased lacrimation (flow of tears).

Other Combinations

Pilocarpine + Timolol

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Frequently asked questions

How does Pilocarpine work?

Pilocarpine enhances acetylcholine activity, increasing secretion from salivary and tear glands, constricting the pupil, and improving aqueous humor outflow, which reduces intraocular pressure.

Does Pilocarpine help with dry eyes?

Yes, Pilocarpine helps alleviate dry eyes by stimulating tear production.

How does Pilocarpine affect heart rate?

Pilocarpine decreases heart rate by enhancing the effects of acetylcholine.

How does Pilocarpine lower intraocular pressure?

Pilocarpine lowers intraocular pressure by constricting the ciliary muscle, which increases fluid outflow from the eye.

Does Pilocarpine increase or decrease heart rate?

Pilocarpine decreases heart rate and does not increase it.

Does Pilocarpine cause blurred vision or hair loss?

Pilocarpine can cause blurred vision but does not lead to hair loss.

Does Pilocarpine cause weight gain or increase blood pressure?

Pilocarpine increases blood pressure, but has no clinically relevant effect on weight.

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