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Pazopanib

Uses

Pazopanib is used in the treatment of kidney cancer and soft tissue sarcoma.

How it Works

How Pazopanib works Pazopanib is an anti-cancer medication that functions by binding to and inhibiting the enzyme receptors known as tyrosine kinases, which are responsible for the proliferation of cancerous cells. Additionally, it restricts the growth of new blood vessels within the tumor, contributing to its effectiveness against cancer.

Side Effects

Common side effects of Pazopanib include headache, diarrhea, high blood pressure, decreased appetite, changes in taste, breathlessness, low blood platelets, decreased levels of thyroid hormones, insomnia (difficulty sleeping), infection, hair loss, nosebleeds, decreased white blood cell count (neutrophils), decreased white blood cell count (lymphocytes), decreased phosphate levels in the blood, dehydration, peripheral sensory neuropathy, blurred vision, hot flushes, venous thromboembolism, voice changes, coughing up blood, increased bilirubin in the blood, liver toxicity, and hypopigmentation.

Other Combinations

Frequently asked questions

Pazopanib should be taken orally once a day, or as directed by your doctor. Swallow the tablets whole with water; do not break or crush them, as this can affect absorption and increase side effects.
Pazopanib should be taken on an empty stomach, at least 1 hour before or 2 hours after meals. Taking it with food may require a dosage increase and can lead to more side effects.
The duration of Pazopanib treatment varies by individual. Your doctor will monitor your condition and determine the appropriate length of treatment. Do not discontinue use without consulting your doctor.
Pazopanib is not a conventional chemotherapy drug; it is a protein kinase inhibitor that prevents the activity of proteins involved in cancer cell growth and spread.
The duration of Pazopanib treatment varies for each individual. Your doctor will monitor your progress and determine how long you should continue taking it. Do not stop without consulting your doctor; continue as long as it remains effective and tolerable.
Yes, avoid grapefruit and grapefruit juice while taking Pazopanib, as they may interfere with the medication's effectiveness. Consult your doctor about other foods to avoid.
Pazopanib can cause severe liver damage. Inform your doctor if you have a history of liver disease. Seek immediate medical attention for symptoms like yellowing of the skin or eyes, dark urine, extreme fatigue, nausea, vomiting, loss of appetite, abdominal pain, or unusual bleeding. Regular lab tests may be required before and during treatment to monitor liver function.
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