Nortriptyline + Pregabalin + Vitamin B12 (Methylcobalamin)

Uses

Pregabalin, Nortriptyline, and Methylcobalamin are used in the treatment of neuropathic pain.

How it Works

How Pregabalin, Nortriptyline, and Methylcobalamin work Pregabalin, Nortriptyline, and Methylcobalamin is a combination of three medications: Pregabalin, Nortriptyline, and Methylcobalamin. Pregabalin is an alpha 2 delta ligand that decreases pain by modulating the calcium channel activity of nerve cells. Nortriptyline is a tricyclic antidepressant that increases the levels of chemical messengers (serotonin and noradrenaline) that inhibit the transmission of pain signals in the brain. Methylcobalamin is a form of vitamin B that aids in the production of myelin, a substance that protects nerve fibers and rejuvenates damaged nerve cells. Together, these medications relieve neuropathic pain, which is pain resulting from damaged nerves.

Side Effects

Common side effects of Pregabalin, Nortriptyline, and Methylcobalamin include constipation, weight gain, orthostatic hypotension (sudden lowering of blood pressure upon standing), increased heart rate, dizziness, sleepiness, tiredness, blurred vision, dry mouth, difficulty urinating, and uncoordinated body movements.

Expert Advice

  • Pregabalin + Nortriptyline + Methylcobalamin is used to treat certain types of chronic pain caused by nerve damage.
  • Inform your doctor if you are taking any other pain-relieving medications.
  • Notify your doctor if you have a history of seizures.
  • Immediately seek medical help if you experience:
    • Hallucinations
    • Fever
    • Sweating
    • Shivering
    • Fast heart rate
    • Muscle twitching
    • Loss of coordination
  • Along with taking Pregabalin + Nortriptyline + Methylcobalamin, your doctor may recommend physiotherapy to relieve pain.

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Frequently asked questions

Regular follow-ups are recommended, especially if symptoms do not improve or if you experience side effects affecting daily activities.
Contact your doctor or seek emergency help immediately, even if there are no symptoms. Overdose symptoms may include drowsiness, confusion, and difficulty breathing.
Pregabalin+Nortriptyline+Methylcobalamin is a combination of three medications used to treat nerve pain (neuropathic pain) by calming damaged or overactive nerves and aiding nerve regeneration.
Yes, it expires. Check the expiry date on the packaging and do not use it past that date.
If you miss a dose and it's almost time for the next one, skip the missed dose. Otherwise, take it as soon as you remember, but do not double up on doses.
Initial benefits may be observed after 2 weeks, but full effects can take 2-3 months or longer.
Yes, it can lead to decreased sexual desire, erectile dysfunction, and reduced satisfaction during intercourse. Discuss any issues with your doctor without discontinuing the medication.
Store tablets in a cool, dry place out of reach of children. Dispose of unused medications properly to prevent accidental ingestion.
No, do not stop taking Pregabalin+Nortriptyline+Methylcobalamin abruptly, even if pain is relieved. Consult your doctor for a gradual tapering plan to avoid withdrawal symptoms.
Yes, this medication may cause drowsiness or unexpected sleep episodes. Avoid driving or operating machinery until you know how it affects you, and inform your doctor of any such episodes.
Avoid alcohol, grapefruit, and activities requiring alertness. Protect yourself from sun exposure as the medication may increase sunburn risk.
To manage potential weight gain, maintain a balanced diet without increasing portion sizes, avoid high-calorie foods, snack on fruits and vegetables, and engage in regular exercise.
No, taking a higher dose may not enhance effectiveness and can increase the risk of serious side effects. Consult your doctor for dose adjustments if needed.
Serious side effects are rare but may include changes in body temperature, difficulty breathing, increased heart rate, mood changes, and signs of infection. Seek medical attention if you experience these symptoms.
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