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Nitroglycerin

Uses

Nitroglycerin is used in the treatment of angina (heart-related chest pain), heart failure, coronary artery disease, hypertensive emergencies, and anal fissures.

How it Works

How Nitroglycerin Works Nitroglycerin is a nitrate that functions by relaxing the blood vessels. This action decreases the oxygen demand of the heart and reduces its workload, thereby preventing or treating angina attacks (chest pain).

Side Effects

Common side effects of Nitroglycerin include dizziness, headache, flushing (a sense of warmth in the face, ears, neck, and trunk), orthostatic hypotension (a sudden drop in blood pressure upon standing), tachycardia, and weakness.

Expert Advice

  • Nitroglycerin may cause dizziness or sleepiness. Do not drive or perform tasks that require concentration until you understand how it affects you.
  • Avoid consuming alcohol while taking Nitroglycerin, as it may increase dizziness.
  • Nitroglycerin may cause headaches, which typically resolve after a few days of continued treatment. Inform your doctor if headaches persist.
  • You may develop tolerance to Nitroglycerin over time, meaning that the same dose may become less effective. Follow the prescribed dosing schedule to minimize this risk.
  • Discontinue the use of medications prescribed for erectile dysfunction, such as sildenafil or tadalafil, while undergoing treatment with Nitroglycerin, as they may lead to low blood pressure.
  • You have been prescribed Nitroglycerin for the prevention and treatment of heart-related chest pain (angina).
  • Adopt a healthy lifestyle by following a low-fat, high-fiber, low-sodium diet, quitting smoking, increasing physical activity, monitoring your weight, and managing stress.

Other Combinations

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Frequently asked questions

What does too much Nitroglycerin do?
Excessive Nitroglycerin can cause low blood pressure, sweating, nausea, vomiting, headache, rapid pulse, weakness, and fainting, requiring emergency medical attention.
Does Nitroglycerin stop heart attacks?
Nitroglycerin helps prevent angina attacks in coronary artery disease by relaxing blood vessels, thus reducing the heart's workload and increasing oxygen supply.
Can I take sildenafil if I am taking Nitroglycerin?
No, combining sildenafil with Nitroglycerin can lead to a dangerous drop in blood pressure.
Can I stop using Nitroglycerin as I feel better now?
Stopping Nitroglycerin suddenly can trigger angina attacks. Consult your doctor for guidance on tapering off the medication safely over 4 to 6 weeks.
What effect does Nitroglycerin have on blood pressure?
Nitroglycerin slightly lowers blood pressure by relaxing blood vessels but is not intended for treating high blood pressure. It may cause lightheadedness, so avoid sudden position changes.
Does the effect of Nitroglycerin wear off after some time?
Yes, overuse can lead to tolerance, reducing its effectiveness. Doctors prescribe the minimum effective dose and schedule doses to prevent tolerance.
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