Nitroglycerin is used in the treatment of angina (heart-related chest pain), heart failure, coronary artery disease, hypertensive emergencies, and anal fissures.
How Nitroglycerin Works Nitroglycerin is a nitrate that functions by relaxing the blood vessels. This action decreases the oxygen demand of the heart and reduces its workload, thereby preventing or treating angina attacks (chest pain).
Common side effects of Nitroglycerin include dizziness, headache, flushing (a sense of warmth in the face, ears, neck, and trunk), orthostatic hypotension (a sudden drop in blood pressure upon standing), tachycardia, and weakness.