Nitisinone

Uses

Nitisinone is used in the treatment of hereditary tyrosinemia type 1.

How it Works

Nitisinone works by inhibiting the breakdown of an amino acid called tyrosine and preventing the accumulation of other toxic substances that can harm your liver or kidneys.

Side Effects

Common side effects of Nitisinone include elevated tyrosine levels, low blood platelets, decreased white blood cell count (lymphocytes), conjunctivitis, corneal opacity, corneal inflammation, photophobia, eye pain, eyelid inflammation, cataract, granulocytopenia, nosebleeds, itching, exfoliative dermatitis, dry skin, maculopapular rash, and hair loss.

Expert Advice

This formulation contains glycerol and may cause:

Headaches
Upset stomach
Diarrhea

Consult your doctor if these symptoms become severe.
Nitisinone may cause:

Vision problems
Eye pain
Eye redness
Burning sensation
Increased sensitivity of eyes to light

Seek immediate medical help in such cases.
You may be prescribed tests to monitor your platelet and white blood cell counts regularly while taking Nitisinone.
Take Nitisinone on an empty stomach at least:

1 hour before a meal
2 hours after a meal

You must avoid certain foods for your treatment to be effective. Follow the diet plan created for you by your doctor.
If you are unable to swallow a capsule whole, open it and sprinkle the medicine into a spoonful of water.
Swallow the mixture right away without chewing. Do not save it for later use.

Other Combinations

Frequently asked questions

Can Nitisinone lead to visual disturbances?

Yes, Nitisinone can cause visual disturbances; avoid driving or operating machinery after taking this medication.

What is the recommended timing for taking Nitisinone?

It is recommended to take Nitisinone at least one hour before or two hours after a meal.

Which foods should be avoided while taking Nitisinone due to high tyrosine content?

While taking Nitisinone, avoid tyrosine-rich foods such as soybeans, chicken, lamb, pork, fish, cheese, eggs, nuts, and beans.

What should I do if I experience diarrhea and stomach pain after starting Nitisinone?

Diarrhea and stomach pain may occur due to the glycerol component in Nitisinone. Contact your doctor if symptoms persist or worsen.

;