Natalizumab

Uses

Natalizumab is used in the treatment of multiple sclerosis (MS).

How it Works

How Natalizumab works Certain immune cells, known as T cells, attack the protective sheath (myelin) surrounding the nerves, leading to disabling effects in multiple sclerosis. Natalizumab functions by binding to T cells and preventing their entry into the brain and spinal cord. This action slows disease progression and reduces the frequency of attacks in multiple sclerosis.

Side Effects

Common side effects of Natalizumab include headache, urinary tract infection, lung infection, pain in extremities, stomach pain, vaginal inflammation, tiredness, joint pain, depression, diarrhea, rash, and throat infection.

Expert Advice

Natalizumab is used to treat multiple sclerosis.
It is administered once every 4 weeks via intravenous infusion, typically in your arm.
This medication may increase your risk of infections.
Inform your doctor immediately if you experience any signs of infection, such as:

Fever
Sore throat
Mouth ulcers
Rash
Severe diarrhea

Notify your doctor if you develop symptoms of liver damage, including:

Abdominal pain
Loss of appetite
Darkened urine
Yellowing of the eyes or skin

Do not discontinue treatment without consulting your doctor.
You are at a higher risk of experiencing an allergic reaction if you resume treatment after a gap of three or more months.