Liquid Paraffin + Magnesium Hydroxide (milk Of Magnesia) + Sodium Picosulfate is a combination laxative used for the short-term relief of constipation. It contains Liquid Paraffin, Magnesium Hydroxide, and Sodium Picosulfate, which work together to soften stools, draw water into the intestines, and stimulate bowel movements. This helps ease stool passage and improve bowel regularity in patients with hard or infrequent stools. It is commonly available as an oral liquid suspension and should be used under medical supervision.

Liquid Paraffin + Magnesium Hydroxide (milk Of Magnesia) + Sodium Picosulfate is a combination laxative used for the short-term management of constipation when dietary measures or single-agent laxatives are not sufficient. It contains Liquid Paraffin, Magnesium Hydroxide, and Sodium Picosulfate, which work together to improve stool passage and restore bowel regularity.

This medicine works through three complementary mechanisms. Liquid Paraffin acts as a lubricant laxative by coating the stool and intestinal wall, which helps retain moisture in the stool and makes it softer and easier to pass. Magnesium Hydroxide works as an osmotic laxative by drawing water into the intestines, increasing stool volume and helping stimulate natural bowel movement. Sodium Picosulfate is a stimulant laxative that is activated in the colon and increases bowel activity by stimulating the intestinal nerve endings, which enhances peristalsis.

Together, these actions help relieve constipation by softening stools, increasing water content in the bowel, and promoting intestinal movement. This leads to easier and more comfortable bowel evacuation, especially in cases of hard stools or infrequent bowel habits.

Liquid Paraffin + Magnesium Hydroxide (milk Of Magnesia) + Sodium Picosulfate is commonly used for short-term relief of constipation and may also be used for bowel cleansing before certain medical procedures when advised by a healthcare professional. It should be used under medical supervision, as prolonged use of stimulant laxatives like Sodium Picosulfate may reduce normal bowel function over time.

Supportive measures such as adequate fluid intake, a fibre-rich diet, and regular physical activity are recommended alongside treatment to help maintain healthy bowel habits and reduce recurrence of constipation.

Liquid Paraffin + Magnesium Hydroxide (milk Of Magnesia) + Sodium Picosulfate may be indicated by your doctor for:

Acute & Chronic Constipation

For the relief of infrequent or difficult bowel movements when dietary fibre and fluid intake are insufficient.

Anorectal Conditions

To ensure soft, effortless stools in patients with anal fissures, haemorrhoids (piles), or hernias, where straining must be avoided.

Pre-operative & Post-operative Care

To clear the bowels before surgery or diagnostic tests, and to manage constipation during the recovery period when physical activity may be limited.

Drug-induced Constipation

To counteract the constipating effects of certain medications, such as opioid painkillers.

Liquid Paraffin + Magnesium Hydroxide (milk Of Magnesia) + Sodium Picosulfate may provide benefits such as:

• Provides a thorough clearing of the bowels through three different laxative pathways.

• Softens hard stools, making them significantly easier and less painful to pass.

• Reduces the need for straining, which protects the pelvic floor and anal tissues.

• Typically produces results within 6 to 12 hours, allowing for predictable relief (often overnight).

• The liquid suspension format allows for easy swallowing and adjustable dosing.

• Effective for clearing the bowel prior to medical examinations or radiological imaging.

Liquid Paraffin + Magnesium Hydroxide (milk Of Magnesia) + Sodium Picosulfate is generally effective, but some users may experience gastrointestinal changes as the bowels are stimulated.

Common side effects of Liquid Paraffin + Magnesium Hydroxide (milk Of Magnesia) + Sodium Picosulfate may include

• Abdominal cramps or mild gripping pain

• Diarrhoea or very loose stools

• Nausea or vomiting

• Flatulence (gas) and bloating

Uncommon side effects of Liquid Paraffin + Magnesium Hydroxide (milk Of Magnesia) + Sodium Picosulfate may include

• Anal irritation (due to frequent or oily stools)

• Dizziness or faintness

Serious side effects that may require immediate medical attention include

• Electrolyte Imbalance: Symptoms like muscle weakness, irregular heartbeat, or extreme thirst due to excessive fluid loss.

• Severe Dehydration: Deep sunken eyes, dry mouth, and significantly decreased urination.

• Lipid Pneumonia: A rare but serious lung condition if Liquid Paraffin is accidentally inhaled into the lungs (aspiration).

• Severe Allergic Reaction: Swelling of the face, rash, or difficulty breathing.

• Always consult your doctor if you notice any persistent or concerning reactions while using Liquid Paraffin + Magnesium Hydroxide (milk Of Magnesia) + Sodium Picosulfate.

Use Liquid Paraffin + Magnesium Hydroxide (milk Of Magnesia) + Sodium Picosulfate exactly as directed by your doctor based on the prescribed form.

• Shake the bottle well before each use to ensure the suspension is properly mixed.

• Use the provided measuring cup or spoon to ensure an accurate dose.

• It is best taken at bedtime so that a bowel movement can be expected the following morning.

• Drink a full glass of water with each dose, and maintain high fluid intake throughout the day to support the osmotic action.

• Do not take this medicine immediately before lying down; remain upright for at least 30 minutes to prevent accidental aspiration of the oil.

• Do not use this medication for more than 7 consecutive days unless specifically instructed by a doctor.

Liquid Paraffin + Magnesium Hydroxide (milk Of Magnesia) + Sodium Picosulfate utilises three mechanisms to treat constipation:

Liquid Paraffin is a mineral oil that works as a lubricant. It stays within the intestinal lumen and coats the stool, preventing the colon from absorbing too much water from the waste. This keeps the stool soft and allows it to slide through the intestines with less resistance.

Magnesium Hydroxide works by osmosis. It is poorly absorbed by the body, so it remains in the intestine and draws water in from the surrounding tissues. This increases the volume of the stool and the pressure within the colon, which naturally triggers the movement of the bowel.

Sodium Picosulfate is a stimulant pro-drug. After it reaches the colon, it is broken down by gut bacteria into its active form. This active compound acts directly on the nerves in the colon wall to increase muscle contractions (peristalsis), pushing the stool toward the rectum for evacuation.

• Taking the dose at night usually ensures a comfortable bowel movement the next morning.

• Hydration is critical; aim for at least 8 glasses of water a day to help the osmotic laxative work effectively.

• Avoid taking this medicine within 2 hours of other oral medications, as it may reduce their absorption.

• Do not use this medicine as a weight-loss tool; laxative abuse can lead to serious health complications.

• Discontinue use and see a doctor if you experience severe abdominal pain or if constipation persists for more than a week.

• Store at room temperature in a cool, dry place.

• Protect from direct sunlight and heat.

• Keep the bottle tightly closed when not in use.

• Do not freeze the suspension.

• Keep out of the reach of children and pets.

• General Diet (NO INTERACTION): Standard food does not interfere with the medication’s action.

• High-Fibre Foods (BENEFICIAL): Consuming fibre-rich foods supports the action of the laxative and promotes natural regularity.

• Antibiotics (MODERATE): Magnesium can bind with antibiotics like Ciprofloxacin or Doxycycline, reducing their effectiveness. Space doses by at least 2 hours.

• Heart Medications (CAUTION): Changes in potassium or magnesium levels can increase the risk of toxicity with medications like Digoxin.

• Diuretics (CAUTION): Using with water pills may increase the risk of dehydration and electrolyte imbalance.

• Intestinal Obstruction (SEVERE): Do not use if a bowel blockage is suspected, as stimulant laxatives can cause severe pain or injury.

• Abdominal Pain (SEVERE): Avoid use if you have undiagnosed stomach pain, nausea, or vomiting.

• Kidney Impairment (CAUTION): Use with caution due to the risk of magnesium accumulation.

• Swallowing Disorders (CAUTION): Increased risk of inhaling the oil into the lungs (aspiration).

An overdose of Liquid Paraffin + Magnesium Hydroxide (milk Of Magnesia) + Sodium Picosulfate may occur if more than the recommended amount is taken or if it is used too frequently.

In most cases, this may lead to excessive bowel activity, resulting in frequent loose stools or diarrhoea, abdominal cramps, and urgency. Because Magnesium Hydroxide and Sodium Picosulfate increase bowel movement, higher-than-needed doses may cause significant fluid loss from the body.

In more pronounced cases, repeated diarrhoea may lead to dehydration and electrolyte imbalance, which can cause weakness, dizziness, or fatigue. Liquid Paraffin may also contribute to excessive oiliness in stools and, rarely, anal leakage if overused.

If an overdose is suspected, it is important to stop the medicine and seek medical advice. Rehydration and supportive care are usually sufficient, as guided by a healthcare professional.

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for a forgotten one.