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Leuprolide

Uses

Leuprolide Uses Leuprolide is used for prostate cancer, endometriosis, uterine fibroids, precocious puberty, and female infertility. It is also used to reduce the thickness of the endometrium of the uterus in preparation for surgery.

How it Works

How Leuprolide works Leuprolide reduces the amount of sex hormones, specifically testosterone in men and estrogen in women. It functions by decreasing blood levels of testosterone in males. Additionally, Leuprolide works by suppressing hormones produced by the ovaries, which leads to a reduction in estrogen levels, one of the hormones responsible for regulating the menstrual cycle in females.

Side Effects

Common side effects of Leuprolide include decreased libido, testicular atrophy, increased sweating, fatigue, muscle weakness, erectile dysfunction, bone pain, hot flashes, and injection site reactions.

Expert Advice

  • Leuprolide is used in the treatment of locally advanced or metastatic prostate cancer.
  • It may also be indicated for the treatment of endometriosis and uterine fibroids.
  • The medication is administered via injection, either subcutaneously or intramuscularly.
  • Possible side effects include dizziness and visual disturbances.
  • Avoid driving or performing tasks that require mental focus until you understand how it affects you.
  • Leuprolide will cause menstrual periods to cease.
  • Menstrual periods are expected to resume 7-12 weeks after the final injection.
  • Consult your doctor if you experience menstrual bleeding despite treatment.
  • Use non-hormonal methods of contraception, such as condoms, to prevent pregnancy during treatment, as this medication may be harmful to a developing fetus.
  • Long-term treatment may lead to bone loss and an increased risk of bone fractures, particularly if you are a heavy drinker, smoker, or have a family history of osteoporosis.

Other Combinations

Frequently asked questions

Yes, Leuprolide may decrease bone mineral density, increasing the risk of weaker bones. Bone density should be assessed in women prior to treatment, and those at risk for osteoporosis may require additional medications for prevention.
Yes, Leuprolide injections can stop menstrual periods by altering reproductive hormones in females. Some may experience vaginal bleeding; consult your doctor if this occurs.
No, Leuprolide is not a chemotherapy medication; it is a synthetic hormone analogue used to treat hormone-dependent conditions in both men and women.
Yes, Leuprolide may elevate blood sugar levels, worsening glucose control in diabetic patients and increasing the risk of developing diabetes. Regular monitoring of blood glucose and HbA1c is recommended, especially for diabetic patients on this medication.
Yes, Leuprolide is a hormonal medication that alters reproductive hormones in females. It is not recommended for use in pregnant women or those who may become pregnant, as it can harm the fetus and may lead to abortion. Inform your doctor if you are pregnant or planning to conceive before starting this medication.
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