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Lemborexant

Uses

Lemborexant is used in the treatment of insomnia.

How it Works

How Lemborexant works Lemborexant inhibits the action of orexin, a chemical that regulates sleep signals in the brain and promotes wakefulness. Once orexin's action is inhibited, the brain no longer receives wake-up signals, which facilitates sleep.

Side Effects

Common side effects of Lemborexant include drowsiness, headache, tiredness, nightmares, and suicidal behaviors.

Expert Advice

  • Lemborexant may cause drowsiness; therefore, patients, particularly the elderly, may be at an increased risk of falls. Caution is advised.
  • Take Lemborexant right before going to bed and only when you can remain in bed for a full night (at least 7 hours).
  • Do not take Lemborexant with other medications that can induce sleepiness, unless directed by your healthcare provider.
  • Never share your medication with anyone else who has a sleep problem.
  • Discuss any unusual or strange thoughts or behaviors with your doctor while using Lemborexant.
  • Stop taking the medication and inform your doctor if you experience complex sleep behaviors, such as:
    • Sleep-walking
    • Sleep-driving
    • Preparing and eating food
    • Making phone calls
    • Engaging in sexual activity while not fully awake
  • Ensure regular visits to your doctor to monitor your progress and any potential side effects.

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Frequently asked questions

Individuals with narcolepsy or those who experience unexpected sleep episodes should avoid Lemborexant, as it may exacerbate their sleep patterns.
Yes, Lemborexant may cause drowsiness, decreased mental alertness, prolonged reaction time, coordination issues, and visual disturbances the following day, increasing the risk of falls. Patients should avoid driving and operating heavy machinery, especially elderly patients.
The safety of Lemborexant during pregnancy is not established; it is advisable to avoid its use in pregnant women to prevent potential risks to the fetus.
Lemborexant should be taken just before bedtime to promote effective sleep.
Lemborexant may interact with other medications. Inform your doctor about all medications you are taking so they can assess potential interactions and adjust dosages or monitor for side effects as necessary.
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