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Itraconazole

Uses

Itraconazole is used in the treatment of fungal infections. It is effective against fungal infections of the mouth or vagina (thrush), skin, and other areas of the body, including fingernails and toenails.

How it Works

Itraconazole is an antifungal medication that works by killing fungi and inhibiting their growth. It accomplishes this by destroying the cell membrane of the fungi, effectively treating skin infections.

Side Effects

Common side effects of Itraconazole include nausea, abdominal pain, and headache.

Expert Advice

  • Itraconazole is used to treat fungal infections of the mouth, skin, vagina, or other parts of the body.
  • Do not skip any doses and complete the full course of treatment, even if you start to feel better.
  • Take it with food, preferably at the same time every day.
  • Use a reliable method of contraception to prevent pregnancy while taking this medication.
  • Avoid taking indigestion remedies (antacids) within two hours of taking Itraconazole.
  • Your doctor may check your liver function before starting treatment and regularly thereafter.
  • Inform your doctor if you notice yellowing of the eyes or skin, dark urine, or stomach pain.
  • Notify your doctor if you experience allergic reactions, nerve pain, or hearing loss.

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Frequently asked questions

What is Itraconazole used for?
Itraconazole is used to treat fungal infections caused by Trichophyton spp., Microsporum spp., and Epidermophyton floccosum, including ringworm, athlete's foot, and groin infections. It also treats persistent nail infections, vaginal and oral candidiasis, cryptococcal infections, and infections caused by histoplasma, aspergillus, and blastomyces.
For how long do I need to take Itraconazole?
The duration of Itraconazole treatment varies based on the type and site of infection. For athlete’s foot, treatment may last 30 days, while for vaginal candidiasis, it may take 1 to 3 days depending on the doctor's advice.
Can I take an antacid and Itraconazole together?
Antacids can reduce stomach acidity, which is necessary for Itraconazole absorption. Avoid taking antacids for at least 2 hours after Itraconazole. If using acid-reducing medications, take Itraconazole with cola.
What should I do if I skip a dose of Itraconazole?
If you miss a dose, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose and resume your regular schedule. Do not double the dose.
Why has my doctor asked me to get blood tests done?
Blood tests may be required to monitor liver function, as Itraconazole can cause serious liver damage. Report any symptoms like loss of appetite, nausea, dark urine, or abdominal pain to your doctor immediately.
What is drug resistance? Is it possible to develop resistance to Itraconazole?
Drug resistance occurs when fungi adapt and become unresponsive to treatment. Some candida species (krusei, glabrata, tropicalis) may exhibit resistance to Itraconazole, so complete the course to minimize this risk.
I am on alprazolam for quite some time. Is it okay if I start Itraconazole now?
Yes, you can take Alprazolam and Itraconazole together, but monitor for side effects like drowsiness. Consult your doctor if you experience any adverse effects after starting Itraconazole.
I am taking Itraconazole for nail infection but there does not seem to be any improvement. Can I stop taking it?
Do not stop taking Itraconazole without completing the prescribed course, as this may prevent full recovery. Nail lesions may take 6-9 months to heal, and new nail growth can take additional time.
My doctor prescribed Itraconazole to me but not to my friend who had a similar fungal infection because she was on dofetilide. Why is it so?
Itraconazole is contraindicated with dofetilide because it can interfere with heart rhythm, posing a risk to patients taking dofetilide.
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