Irinotecan
Uses
Irinotecan is used in the treatment of colon and rectal cancer.
How it Works
How Irinotecan works Irinotecan is an anti-cancer medication that functions by inhibiting the activity of an enzyme called topoisomerase I, which is involved in the DNA replication of cancer cells. This action slows the growth of cancer cells and ultimately leads to their death.
Side Effects
Common side effects of Irinotecan include fatigue, nausea, vomiting, weakness, hair loss, fever, anemia (low red blood cell count), diarrhea, decreased white blood cell count (neutrophils), decreased appetite, and mucosal inflammation.
Expert Advice
- Irinotecan is used in combination with other medications for the treatment of metastatic cancer of the colon and rectum.
- It is administered via a drip into a vein (intravenous infusion).
- Possible side effects include dizziness and visual disturbances.
- Do not drive or engage in activities that require mental focus until you understand how this medication affects you.
- Use a reliable contraceptive method to prevent pregnancy while taking this medication.
- Your doctor may conduct regular blood tests to monitor blood cells, as well as kidney and liver function during treatment.
- Inform your doctor immediately if you notice any signs of infection, such as fever, sore throat, or rash.
- Notify your doctor if you experience any of the following: passage of blood in stools, dizziness or faintness, continuous episodes of nausea, vomiting, diarrhea, or fever.
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