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Infliximab

Uses

Infliximab is used in the treatment of ulcerative colitis, Crohn's disease, psoriasis, ankylosing spondylitis, and rheumatoid arthritis.

How it Works

Infliximab is a monoclonal antibody that blocks a protein in the immune system called TNF (tumor necrosis factor), which causes inflammation, including pain and swelling, in the joints.

Side Effects

Common side effects of Infliximab include headache, sinus inflammation, upper respiratory tract infection, abdominal pain, nausea, pharyngitis, infusion site reaction, infection, auto-antibody formation, and anemia (low number of red blood cells).

Expert Advice

  • Infliximab is administered via intravenous infusion under the supervision of a doctor.
  • It is typically given at the following intervals:
    • 0 weeks
    • 2 weeks
    • 6 weeks
    • Once every 8 weeks thereafter
  • It may take some time before you start to feel better after receiving this medication.
  • It is crucial not to miss any doses and to attend your next infusion as scheduled by your doctor.
  • Infliximab can impair your body's ability to fight infections. Notify your doctor if you experience:
    • Fever
    • Cough
    • Runny nose
    • Rash
    • Loose stools
    • Flu-like symptoms
  • Inform your doctor if you have ever had tuberculosis or if you have been in close contact with someone who has or had tuberculosis.
  • Your doctor may recommend specific tests to screen for tuberculosis before initiating treatment with this medication.
  • Inform your doctor if you have or have ever had a hepatitis B virus infection.
  • Your doctor may test you for hepatitis B virus before starting treatment with this medication.
  • You may be advised to undergo regular blood tests to monitor blood counts while taking this medication.

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Frequently asked questions

Infliximab can weaken the immune system, increasing the risk of serious infections that may require hospitalization. Your doctor will monitor you for signs of infection before and during treatment. There are also reports suggesting a potential increased risk of certain cancers. Your doctor prescribes this medication based on a careful assessment of the benefits versus risks. Consult your doctor with any concerns.
Infliximab is administered as an intravenous infusion in a hospital setting, typically over a two-hour period under professional supervision. After the initial treatment, subsequent infusions are scheduled at two weeks, four weeks, and then every eight weeks. Please consult your doctor for a personalized schedule.
Infliximab may cause heart issues, including heart attack, decreased blood flow, or abnormal heart rhythms, typically within 24 hours of infusion. Symptoms can include chest discomfort, pain, shortness of breath, dizziness, and swelling. Contact your doctor immediately if you experience any of these symptoms.
Yes, in rare cases, Infliximab can affect the liver. Contact your doctor if you experience fever, dark urine, severe fatigue, right-sided abdominal pain, or jaundice (yellowing of the skin and eyes).
Yes, Infliximab is an immunosuppressant that reduces inflammation caused by the immune system in conditions like rheumatoid arthritis. It works by binding to tumor necrosis factor (TNF alpha), a protein responsible for inflammation, which helps alleviate pain and swelling.
While alcohol does not directly interfere with Infliximab, it is advisable to avoid it. Discuss any concerns with your doctor.
Symptom relief varies by individual, but most patients notice improvement within two weeks, with maximum benefits often observed after four weeks.
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