Hyaluronidase

Uses

Hyaluronidase is used as a preservative.

How it Works

Hyaluronidase works by increasing the permeability of connective tissue through the hydrolysis of hyaluronic acid. It hydrolyzes hyaluronic acid by splitting the glucosaminidic bond between C1 of the glucosamine moiety and C4 of glucuronic acid. This process temporarily decreases the viscosity of the cellular cement and enhances the diffusion of injected fluids or localized transudates and exudates, thereby facilitating their absorption.

Expert Advice

  • Hyaluronidase aids in the absorption of injections administered into a muscle or under the skin.
  • It may also facilitate the reabsorption of excess fluids and blood in the tissues.
  • Your doctor or nurse will administer the injection either into a muscle or subcutaneously.
  • Potential side effects include temporary irritation, swelling, or bruising at the injection site.
  • Notify your doctor if any of these symptoms persist.
  • Inform your doctor if you are pregnant or breastfeeding.

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