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Goserelin acetate

Uses

Goserelin acetate is used in the treatment of prostate cancer, breast cancer, endometriosis, uterine fibroids, precocious puberty, and female infertility. It is also employed to reduce the thickness of the endometrium in preparation for surgery.

How it Works

How Goserelin acetate works Goserelin acetate is a hormone similar to the one produced by the hypothalamus gland in the brain. It functions by reducing blood levels of testosterone in males.

Side Effects

Common side effects of Goserelin acetate include decreased libido, erectile dysfunction, depression, headache, dizziness, nausea, high blood pressure, breast atrophy, pain during sexual intercourse, hot flushes, sexual dysfunction, urinary tract disorder, lethargy, pain, edema (swelling), upper respiratory tract infection, rash, sweating, decreased appetite, chronic obstructive pulmonary disease (COPD), heart failure, insomnia (difficulty sleeping), vaginal inflammation, emotional lability, acne, breast enlargement, pelvic discomfort, and application site reactions (burning, irritation, itching, and redness). Additional side effects may include pain during periods and uterine bleeding.

Expert Advice

  • Goserelin acetate is used for the treatment of:
    • Prostate cancer in men
    • Breast cancer in women
    • Endometriosis in women
    • Uterine fibroids in women
  • It may also be used in conjunction with other medications to treat infertility in women.
  • Goserelin acetate is administered via a prefilled syringe, injected subcutaneously into the abdomen every 28 days.
  • This medication may lead to a reduction in bone mineral density and weakened bones.
  • Your doctor may prescribe additional medications to mitigate bone loss.
  • Inform your doctor if you experience symptoms of depression or have disturbing thoughts or feelings during treatment with this medication.
  • Vaginal bleeding may occur in the first month after initiating treatment and typically resolves on its own.
  • Notify your doctor if the bleeding persists.

Other Combinations

Related Medications

Frequently asked questions

Goserelin acetate implants contain the active ingredient Goserelin acetate and are administered via injection under the skin of the abdomen.
Zoladex can be administered once or multiple times as needed. Consult your doctor for personalized advice regarding the duration of treatment.
Goserelin acetate is a chemotherapeutic agent used to treat hormone-sensitive cancers, such as breast cancer in pre- and peri-menopausal women and prostate cancer, as well as certain benign gynecological disorders like endometriosis and uterine fibroids. It is also used in assisted reproduction and to treat precocious puberty.
Yes, you can safely take paracetamol, ibuprofen, or norethisterone alongside Zoladex.
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