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Gabapentin + Nortriptyline

Uses

Gabapentin and Nortriptyline are used in the treatment of neuropathic pain.

How it Works

How Gabapentin and Nortriptyline work Gabapentin and Nortriptyline is a combination of two medicines: Gabapentin and Nortriptyline. Gabapentin is an alpha-2 delta ligand that reduces pain by modulating the calcium channel activity of nerve cells. Nortriptyline is a tricyclic antidepressant that increases the levels of chemical messengers (serotonin and noradrenaline) that inhibit the transmission of pain signals in the brain. Together, they provide relief from neuropathic pain, which is pain resulting from damaged nerves.

Side Effects

Common side effects of Gabapentin and Nortriptyline include constipation, difficulty urinating, weight gain, sleepiness, dizziness, tiredness, blurred vision, dry mouth, orthostatic hypotension (sudden drop in blood pressure upon standing), increased heart rate, and uncoordinated body movements.

Expert Advice

  • Gabapentin + Nortriptyline is used to treat specific types of chronic pain resulting from nerve damage.
  • Inform your doctor if you are taking any other pain-relieving medications.
  • In conjunction with this medication, your doctor may recommend physiotherapy to help alleviate pain.
  • Avoid taking antacids 2 hours before or after administering Gabapentin + Nortriptyline, as they can hinder the absorption of the medication.

Other Combinations

Baclofen + Gabapentin + Lidocaine (Lignocaine)

Gabapentin + Nortriptyline + Vitamin B12 (Methylcobalamin)

Gabapentin + Lidocaine (Lignocaine)

Gabapentin + Vitamin B12 (Methylcobalamin)

Alpha Lipoic Acid + Gabapentin + Vitamin B12 (Methylcobalamin)

Capsaicin + Gabapentin + Ketoprofen + Methyl Salicylate

Diclofenac + Gabapentin + Methyl Salicylate

Frequently asked questions

Gabapentin+Nortriptyline is a combination of Gabapentin and Nortriptyline, used to treat nerve pain (neuropathic pain) by calming overactive nerves in the brain, thereby reducing pain sensation.
Contact your doctor or seek emergency help immediately, even if you feel fine. Overdose symptoms may include drowsiness, confusion, and difficulty breathing.
Yes, it may lead to decreased sexual desire, erectile dysfunction, and reduced satisfaction during intercourse. Discuss any issues with your doctor without discontinuing the medication.
Initial benefits may be seen after 2 weeks, but it can take 2-3 months or longer for full effects to be realized.
Avoid driving and alcohol, as they can impair your alertness and increase side effects. Grapefruit and grapefruit juice may interact with the medication, and protect yourself from sun exposure.
Yes, Gabapentin+Nortriptyline may cause drowsiness or sudden sleep episodes. Avoid driving or operating machinery until you understand how the medication affects you, and inform your doctor if you experience such episodes.
Store tablets in their original packaging in a cool, dry place, out of reach of children. Dispose of unused medications safely to prevent accidental ingestion.
If you miss a dose and it's close to the next one, skip it. If it's not close, take it as soon as you remember. Do not double the dose to make up for a missed one.
No, do not stop taking Gabapentin+Nortriptyline even if your pain improves. Consult your doctor for a gradual tapering plan to avoid withdrawal symptoms such as anxiety, nausea, and pain.
Prevent weight gain by maintaining a balanced diet, avoiding high-calorie foods, and exercising regularly. Focus on healthy snacks like fruits and vegetables to curb hunger between meals.
Serious side effects are rare but can include changes in body temperature, difficulty breathing, heart palpitations, mood changes, and vision problems. Seek immediate medical attention if you experience these symptoms.
Regular check-ups may be necessary, especially if your symptoms do not improve or if side effects disrupt your daily activities.
No, exceeding the recommended dose does not enhance effectiveness and may increase the risk of serious side effects. Consult your doctor if your symptoms worsen despite taking the recommended dose.
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