Gabapentin + Nortriptyline

Uses

Gabapentin and Nortriptyline are used in the treatment of neuropathic pain.

How it Works

How Gabapentin and Nortriptyline work Gabapentin and Nortriptyline is a combination of two medicines: Gabapentin and Nortriptyline. Gabapentin is an alpha-2 delta ligand that reduces pain by modulating the calcium channel activity of nerve cells. Nortriptyline is a tricyclic antidepressant that increases the levels of chemical messengers (serotonin and noradrenaline) that inhibit the transmission of pain signals in the brain. Together, they provide relief from neuropathic pain, which is pain resulting from damaged nerves.

Side Effects

Common side effects of Gabapentin and Nortriptyline include constipation, difficulty urinating, weight gain, sleepiness, dizziness, tiredness, blurred vision, dry mouth, orthostatic hypotension (sudden drop in blood pressure upon standing), increased heart rate, and uncoordinated body movements.

Expert Advice

Other Combinations