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Efavirenz + Lamivudine + Tenofovir disoproxil fumarate

Uses

Lamivudine, Tenofovir disoproxil fumarate, and Efavirenz are used in the treatment of HIV infection.

How it Works

How Lamivudine, Tenofovir disoproxil fumarate, and Efavirenz work Lamivudine, Tenofovir disoproxil fumarate, and Efavirenz is a combination of three antiviral medications. They work by preventing the HIV virus from multiplying, thereby reducing the viral load in your body. Additionally, they help increase the CD4 cell count, which are white blood cells that protect against infections.

Side Effects

Common side effects of Lamivudine, Tenofovir disoproxil fumarate, and Efavirenz include headache, dizziness, nausea, insomnia (difficulty sleeping), weakness, depression, diarrhea, rash, pain, fever, decreased white blood cell count (neutrophils), peripheral neuropathy (tingling and numbness in the feet and hands), back pain, abdominal pain, anxiety, vomiting, joint pain, pneumonia, dyspepsia, muscle pain, lipodystrophy (skin thickening or pits at the injection site), hypercholesterolemia (high cholesterol), increased triglyceride levels in the blood, elevated creatinine kinase, elevated levels of serum amylase, blood in urine, increased transaminase levels in the blood, cough, impaired concentration, and abnormal dreams.

Expert Advice

  • Lamivudine + Tenofovir disoproxil fumarate + Efavirenz is a combination of three medications that slows down or halts the progression of HIV infections.
  • Take the medication on an empty stomach, preferably at bedtime, to minimize side effects.
  • Skipping doses increases the risk of treatment failure; ensure that you take all doses at the correct times.
  • Lamivudine + Tenofovir disoproxil fumarate + Efavirenz may cause dizziness or sleepiness.
  • Avoid driving or engaging in activities requiring concentration until you know how the medication affects you.
  • This combination therapy can lead to birth defects; therefore, use effective contraception while taking Lamivudine + Tenofovir disoproxil fumarate + Efavirenz and for 12 weeks after discontinuation.
  • It may cause weakening of your bones; exercise regularly and consider taking calcium and vitamin D supplements as recommended by your doctor.
  • Your doctor may monitor your kidney and liver functions regularly.
  • Inform your doctor if you experience symptoms such as abdominal pain, loss of appetite, darkened urine, or yellowing of the eyes or skin.
  • Do not discontinue Lamivudine + Tenofovir disoproxil fumarate + Efavirenz without consulting your doctor.

Other Combinations

Efavirenz + Emtricitabine + Tenofovir disoproxil fumarate

Efavirenz + Lamivudine + Stavudine

Efavirenz + Lamivudine + Zidovudine

Didanosine + Efavirenz + Lamivudine

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