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Donepezil + Memantine

Uses

Donepezil and Memantine are used in the treatment of Alzheimer's disease.

How it Works

How Donepezil and Memantine Work Donepezil and Memantine is a combination of two medications used to treat Alzheimer’s disease. Donepezil is a cholinesterase inhibitor, while Memantine is an NMDA receptor antagonist. Together, they help balance the levels of chemical messengers in the brain and support the transmission of nerve signals.

Side Effects

Common side effects of Donepezil and Memantine include nausea, diarrhea, headache, dizziness, insomnia (difficulty sleeping), weight loss, drug allergy, balance disorder (loss of balance), high blood pressure, and breathlessness.

Expert Advice

  • Donepezil + Memantine is used for the symptomatic treatment of Alzheimer's disease.
  • It does not cure Alzheimer's but may help improve brain function and daily activities.
  • Take it with food to avoid an upset stomach.
  • Drink plenty of fluids to stay hydrated while taking this medicine.
  • Monitor your body weight regularly, as both Donepezil + Memantine and Alzheimer's disease can cause weight loss.
  • Avoid driving or engaging in activities that require mental focus until you understand how it affects you.
  • Inform your doctor if you have a history of seizures, as it may increase the risk of seizures if you have experienced them in the past.
  • It may cause stomach ulcers, especially if you are also taking medications for inflammation or pain.
  • Contact your doctor if you experience vomiting blood or have black-colored stools.

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Frequently asked questions

Yes, Donepezil+Memantine may cause diarrhea. If diarrhea occurs, consult your doctor before taking any additional medications.
Donepezil+Memantine is contraindicated for individuals allergic to Memantine, Donepezil, or any of their components. Discuss your complete medical history with your doctor before use.
Store Donepezil+Memantine in its original packaging, tightly closed, and as directed on the label. Safely dispose of any unused medicine to prevent accidental ingestion by pets, children, or others.
Before taking Donepezil+Memantine, inform your doctor about all past and present medical conditions, including heart, lung, liver, kidney, or bladder issues, seizures, stomach ulcers, and any upcoming medical procedures. Also, disclose all medications currently being taken.
In case of an overdose of Donepezil+Memantine, immediately visit the nearest medical emergency department or contact your doctor.
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