Dimethyl fumarate is used in the treatment of multiple sclerosis (MS).
How Dimethyl fumarate works Dimethyl fumarate is an Nrf2 activator. It functions by suppressing the inflammation and immune responses that lead to nerve damage in multiple sclerosis.
Common side effects of Dimethyl fumarate include flushing (a sense of warmth in the face, ears, neck, and trunk), nausea, diarrhea, nasopharyngitis (inflammation of the throat and nasal passages), urinary tract infection, upper respiratory tract infection, abdominal pain, protein in urine, vomiting, itching, rash, hot flashes, increased alanine aminotransferase, gastroenteritis, dyspepsia, erythema (skin redness), microalbuminuria, dryness of the mouth, hypersensitivity, weight loss, allergic dermatitis, otitis media (ear infection), and lymphocytopenia.