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Crizotinib

Uses

Crizotinib is used in the treatment of non-small cell lung cancer.

How it Works

How Crizotinib Works Crizotinib is an anti-cancer medication that functions by blocking the action of an abnormal protein that signals cancer cells to multiply. This mechanism helps to stop or slow the spread of cancer cells.

Side Effects

Common side effects of Crizotinib include dizziness, fatigue, edema (swelling), decreased appetite, vision disorders, gastrointestinal toxicity, increased transaminase levels in the blood, upper respiratory tract infections, neuropathy, and abnormal blood cell counts.

Expert Advice

  • Crizotinib aids in the treatment of non-small cell lung cancer that is locally advanced or has metastasized to other areas of the body.
  • Take it at the same time each day, with or without food.
  • Possible side effects include:
    • Diarrhea
    • Nausea
    • Vomiting
  • Stay hydrated and inform your doctor if gastrointestinal symptoms persist.
  • It may cause dizziness or blurred vision. Avoid driving or engaging in activities that require concentration until you know how it affects you.
  • Inform your doctor if you experience any of the following:
    • Severe stomach pain
    • Fever
    • Chills
    • Shortness of breath
    • Fast heartbeat
    • Partial or complete loss of vision
    • Changes in bowel habits
  • Your doctor may require regular blood tests to monitor liver function during treatment with this medication.
  • Do not take Crizotinib if you are pregnant or breastfeeding.
  • Use reliable methods of contraception to prevent pregnancy while taking this medication.

Other Combinations

Related Medications

Frequently asked questions

Crizotinib inhibits the enzyme tyrosine kinase, which is responsible for signaling the growth and spread of cancer cells.
Crizotinib is used to treat non-small-cell lung cancer associated with mutations in the anaplastic lymphoma kinase gene in patients who have not responded to prior therapies.
Crizotinib is administered orally in capsule form.
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