Crizanlizumab
Uses
Crizanlizumab is used in the treatment of sickle cell anemia.
How it Works
How Crizanlizumab works Crizanlizumab functions by binding to a protein known as P-selectin, which causes blood cells to adhere to one another. By blocking this protein, Crizanlizumab prevents blood cells from clumping together and sticking to the walls of blood vessels. This mechanism enhances blood flow throughout the body and reduces the risk of pain crises and other severe complications associated with sickle cell disease, such as stroke and organ damage.
Side Effects
Common side effects of Crizanlizumab include nasopharyngitis (inflammation of the throat and nasal passages), upper respiratory tract infection, rash, flu, dermatitis, bronchitis (inflammation of the airways), eczema, swelling of lymph nodes, and oropharyngeal pain.
