ChAdOx1 nCoV-19 Corona Virus Vaccine (Recombinant)

Uses

ChAdOx1 nCoV-19 Corona Virus Vaccine (Recombinant) is used to prevent coronavirus disease (COVID-19).

How it Works

How ChAdOx1 nCoV-19 Corona Virus Vaccine (Recombinant) works ChAdOx1 nCoV-19 Corona Virus Vaccine (Recombinant) contains a non-replicating virus, a weakened chimpanzee adenovirus that causes the common cold, which is genetically engineered to produce coronavirus proteins in the body. The virus is weakened and cannot cause disease. This vaccine provides active immunization against Covid-19 infection, helping the body to fight the virus if exposed. As a result, there is a reduced risk of developing the illness and its associated consequences.

Side Effects

Common side effects of the ChAdOx1 nCoV-19 Corona Virus Vaccine (Recombinant) include headache, nausea, vomiting, muscle pain, joint pain, injection site reactions (such as pain, swelling, and redness), fatigue, discomfort, fever, chills, and flu-like symptoms.

Expert Advice

  • ChAdOx1 nCoV-19 Corona Virus Vaccine (Recombinant) is a 2-dose vaccination regimen.
  • The second dose is administered between 12 to 16 weeks after the first dose.
  • ChAdOx1 nCoV-19 Corona Virus Vaccine (Recombinant) is typically given intramuscularly in the upper arm.
  • Vaccination is voluntary; however, completing the vaccination schedule is advisable to limit the spread of the virus.
  • It is recommended to get vaccinated even if you have previously recovered from a COVID-19 infection, as this can enhance your immune response.
  • Have a proper meal before visiting the vaccination site; do not get vaccinated on an empty stomach.
  • Individuals with confirmed or suspected COVID-19 infection should defer vaccination for 14 days after symptom resolution to minimize the risk of spreading the infection at the vaccination site.
  • A minimum interval of 14 days should be maintained between the administration of any other vaccine.
  • If the benefits of vaccination outweigh the potential unknown risks of coadministration, COVID-19 and other vaccines may be administered within a shorter period (e.g., tetanus vaccine, rabies vaccine, etc.).
  • You may be monitored at the vaccination center to guard against any immediate allergic reactions or side effects.
  • In addition to vaccination, continue to observe other control measures such as social distancing, wearing masks, and hand-washing.
  • ChAdOx1 nCoV-19 Corona Virus Vaccine (Recombinant) is currently not recommended for children, as safety and efficacy have not yet been established.

Other Combinations

Frequently asked questions

COVID-19, or coronavirus disease 2019, is a highly infectious illness caused by the SARS-CoV-2 virus. Symptoms include breathing difficulties, fever, and cough, and it spreads rapidly from person to person.
Emergency Use Authorization (EUA) is a declaration by Indian regulators allowing the use of certain vaccines, medicines, or devices during a public health emergency, weighing their benefits against associated risks while ongoing assessments of safety and effectiveness are conducted.
Individuals with a history of severe allergic reactions to previous COVID-19 vaccines or injectable therapies should not receive ChAdOx1 nCoV-19. Pregnant and lactating women have not been included in clinical trials, so they should consult a doctor before vaccination.
Yes, you can still get vaccinated without pre-registration. Visit your nearest Government healthcare worker for guidance on the nearest COVID-19 Vaccination Centre (CVC), and bring your mobile phone and photo ID. CVC staff will assist with on-the-spot registration and vaccination.
There has been no direct comparison between ChAdOx1 nCoV-19 and Covaxin in India, so it is not possible to declare one as better. Both vaccines are effective in preventing COVID-19, especially in vulnerable populations.
You can register online for a vaccination appointment through the Co-WIN portal by providing basic information and photo ID details. One mobile number can register up to four people, but each must have their own ID.
Five vaccines granted EUA in India are Covishield, Covaxin, Sputnik V, Moderna, and Johnson & Johnson’s single-dose vaccine.
ChAdOx1 nCoV-19 vaccine trials for children are ongoing, and there is currently insufficient evidence to recommend its use in this population. Both ChAdOx1 nCoV-19 and Covaxin have not been studied for safety and effectiveness in children. Therefore, it is advised not to vaccinate children until more data is available.
The second dose of ChAdOx1 nCoV-19 vaccine is administered 12-16 weeks after the first dose, as this interval increases vaccine efficacy to 79%. The gap was previously 4-6 weeks but has been extended based on new data.
Yes, individuals who have previously been infected with COVID-19 should still receive vaccination unless advised otherwise by their healthcare provider. The vaccine serves as a booster to enhance the immune response, and reinfections can occur, making vaccination important.
ChAdOx1 nCoV-19 vaccine must be stored and transported at 2°C to 8°C, with the cold chain maintained through active and passive equipment at approximately 29,000 cold chain points across India.
Common side effects of ChAdOx1 nCoV-19 vaccine include injection site pain, headache, fatigue, muscle pain, malaise, fever, chills, joint pain, and nausea. Rarely, demyelinating disorders have been reported, but a causal relationship has not been established.
Yes, ChAdOx1 nCoV-19 vaccine has undergone the necessary clinical trials prior to receiving Emergency Use Authorization (EUA).
According to the Government of India guidelines, COVID-19 frontline workers receive vaccination on priority. Family members will be vaccinated based on age-specific prioritization set by the Government of India.
Yes, vaccines are expected to provide reasonable protection against newer strains of COVID-19. The immune response generated by vaccination creates multiple types of antibodies, which are effective against the virus, including its mutations.
Yes, ChAdOx1 nCoV-19 is safe and effective for adults with comorbidities like hypertension, diabetes, chronic kidney disease, heart disease, and lipid disorders. It is particularly beneficial for those with such conditions, but consult your doctor if you have specific concerns.
It typically takes 2-3 weeks after completing the vaccination schedule (after the second dose) for adequate antibody levels to develop.
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