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Ceritinib

Uses

Ceritinib is used in the treatment of non-small cell lung cancer.

How it Works

How Ceritinib works Ceritinib is an anti-cancer medication that works by blocking the action of the abnormal protein responsible for signaling cancer cells to multiply. This mechanism helps to stop or slow the spread of cancer cells.

Side Effects

Common side effects of Ceritinib include fatigue, nausea, vomiting, and diarrhea.

Expert Advice

  • Take it with or without food, preferably at the same time each day.
  • Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it does not stop or if you notice blood in your stools.
  • Use a reliable contraceptive method to prevent pregnancy while taking this medicine and for one month after discontinuation.
  • Monitor your blood pressure regularly while on this medication.
  • Inform your doctor if you experience symptoms of very high blood pressure, such as:
    • Severe headache
    • Confusion
    • Vision problems
    • Nausea
    • Vomiting
  • This medication may cause serious bleeding problems. Inform your doctor if you experience:
    • Headaches
    • Stomach pain
    • Blood in your urine or stools
  • Do not take this medicine if you are pregnant, planning to conceive, or breastfeeding.

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Frequently asked questions

Ceritinib is a cancer medication containing the active substance ceritinib, used to treat patients with anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC).
ALK-positive NSCLC is a type of lung cancer caused by abnormal behavior and multiplication of cells with a mutated anaplastic lymphoma kinase (ALK) gene.
Take Ceritinib on an empty stomach, avoiding food for 2 hours before and after the dose. Consult your doctor if you have any questions.
Yes, Ceritinib may cause vision issues. Regular eye exams are recommended, and you should report any changes in vision or blurred vision to your doctor.
Ceritinib treats ALK-positive NSCLC that has metastasized by blocking the abnormal ALK gene, which shrinks tumors and inhibits further growth.
Continue taking Ceritinib as prescribed until your doctor advises otherwise. Regular scans will assess tumor response to treatment, with scheduling determined by your doctor.
Yes, serious side effects may include rapid or irregular heartbeat, chest pain, lung inflammation (pneumonitis), liver disease, or severe diarrhea. Your doctor may adjust or pause treatment if necessary.
Yes, Ceritinib may cause lung inflammation (pneumonitis). Notify your doctor immediately if you experience new or worsening symptoms like shortness of breath, difficulty breathing, cough, or fever.
Ceritinib may elevate blood sugar levels. Monitor your blood sugar regularly and consult your doctor if you experience excessive thirst, hunger, frequent urination, headaches, or difficulty concentrating.
Consume foods high in soluble fiber, such as ripe bananas, oranges, boiled potatoes, white rice, curd, and oatmeal to help relieve diarrhea. Stay hydrated by drinking 8-10 glasses of water daily and consider soups and juices.
Look for signs of liver issues, such as excessive fatigue, yellowing of skin or eyes, dark urine, nausea, vomiting, loss of appetite, itching, easy bruising, or right abdominal pain. Consult your doctor immediately if you experience any of these symptoms.
Use a moisturizer for rashes, dry, and itchy skin. Wear loose cotton clothing and maintain a comfortable room temperature. These issues typically resolve after stopping treatment, but inform your doctor if you experience yellowing of the skin, as it may indicate liver problems.
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