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Carbidopa + Entacapone + Levodopa

Uses

Levodopa, Carbidopa, and Entacapone Uses Levodopa, Carbidopa, and Entacapone are used in the treatment of Parkinson's disease.

How it Works

How Levodopa, Carbidopa, and Entacapone work Levodopa, Carbidopa, and Entacapone is a combination of three medications used to treat Parkinsonism. Levodopa is a precursor to dopamine, a chemical messenger that controls movement in the brain. Carbidopa is a peripheral decarboxylase inhibitor that prevents the breakdown of Levodopa, allowing it to enter the brain and increase dopamine levels. Entacapone is a COMT inhibitor that results in higher and more sustained levels of Levodopa in the blood, leading to greater relief from the symptoms of Parkinson’s disease.

Side Effects

Common side effects of Levodopa, Carbidopa, and Entacapone include urine discoloration, headache, dry mouth, insomnia (difficulty sleeping), anxiety, dizziness, abnormal dreams, involuntary muscle movements, and gastrointestinal disturbances.

Expert Advice

  • You have been prescribed Levodopa + Carbidopa + Entacapone to treat your symptoms of Parkinson's disease.
  • Avoid a high-protein diet (e.g., meat, poultry, and dairy products) while taking this medication, as it can reduce the amount of medication absorbed by your body.
  • This medication may cause dizziness or sleepiness. Do not drive or engage in activities requiring concentration until you know how it affects you.
  • To reduce the risk of feeling dizzy or fainting, rise slowly if you have been sitting or lying down.
  • Do not stop taking the medication suddenly without consulting your doctor, as this may result in a serious syndrome characterized by fever, stiff muscles, unusual body movements, sweating, and confusion.
  • Contact your doctor if you experience hallucinations or notice any changes in your behavior.

Other Combinations

Carbidopa + Levodopa

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