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Capmatinib

Uses

Capmatinib is used in the treatment of non-small cell lung cancer.

How it Works

Capmatinib works by inhibiting the action of an abnormal protein that promotes the proliferation of cancer cells. This mechanism helps to slow or halt the spread of cancer cells.

Side Effects

Common side effects of Capmatinib include edema (swelling), nausea, musculoskeletal stiffness, breathlessness, fatigue, vomiting, cough, and decreased appetite.

Expert Advice

  • Notify your healthcare provider immediately if you experience any new or worsening symptoms, including cough, fever, or difficulty breathing/shortness of breath.
  • Avoid pregnancy and use contraceptives during treatment and for 1 week after your last dose of Capmatinib.
  • Your skin may become sensitive to sunlight during treatment with this medication. Use sunscreen or wear protective clothing to limit direct sunlight exposure.
  • To alleviate nausea, take antinausea medications as prescribed by your doctor and consume small, frequent meals.
  • Swelling of the hands or feet is a common side effect of Capmatinib. Your doctor may recommend leg elevation or dietary salt modification to relieve swelling symptoms.
  • Drink at least two to three quarts of fluid every 24 hours unless otherwise instructed by your healthcare provider.
  • Inform your doctor about all medications you are taking, including prescription and over-the-counter drugs, vitamins, and herbal supplements.

Other Combinations

Related Medications

Frequently asked questions

How often should I take Capmatinib?
Capmatinib should be taken twice daily, with or without food, unless otherwise directed by your doctor. Do not alter the dosage or stop taking it without consulting your doctor.
Can Capmatinib be taken during pregnancy?
Capmatinib may harm a developing fetus. It is crucial to avoid conception during treatment and for one week after the last dose. Discuss effective contraception with your doctor before starting.
What is Capmatinib and what is its purpose?
Capmatinib is a prescription medication used to treat adults with metastatic non-small cell lung cancer (NSCLC) that cannot be surgically removed and has an abnormal gene.
Is Capmatinib considered a targeted therapy?
Yes, Capmatinib is the first targeted therapy specifically designed for patients with metastatic NSCLC that has a mutation causing MET exon 14 skipping.
What precautions should I take while on Capmatinib?
During treatment, your skin may become more sensitive to sunlight. It is advisable to use sunscreen and wear protective clothing to minimize sun exposure.
What tests are required before starting Capmatinib?
A liver function test will be conducted before and during treatment. Notify your doctor immediately if you experience signs of liver issues, such as jaundice, nausea, vomiting, loss of appetite, dark urine, or abdominal pain.
Are nausea and fatigue common side effects of Capmatinib?
Yes, nausea and fatigue are common side effects. To alleviate nausea, eat smaller, more frequent meals and avoid salty, spicy, fried, or fatty foods. Rest and light exercise can help reduce fatigue.
Which is more effective, targeted therapy or chemotherapy?
Both chemotherapy and targeted therapy are effective cancer treatments. Chemotherapy can damage normal cells along with cancer cells, whereas targeted therapy selectively attacks cancer cells without harming normal cells.
Should I avoid certain foods and drinks while on Capmatinib?
You can maintain your regular diet unless advised otherwise by your doctor. It is recommended to stay hydrated, eat small, nutritious snacks, and consider hard candies or popsicles to mitigate nausea.
Is swelling in the lower legs and ankles a concern while taking Capmatinib?
Swelling may occur during treatment. Inform your doctor, as they may need to adjust your dosage or modify your treatment plan based on your symptoms.
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