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Bicalutamide

Uses

Bicalutamide is used in the treatment of prostate cancer, polycystic ovarian syndrome (PCOS), and excessive hair growth.

How it Works

How Bicalutamide works Bicalutamide inhibits the effects of natural male hormones on the growth of prostate cells. Additionally, it prevents the unwanted effects of androgens in females, such as excessive hair growth and acne.

Side Effects

Common side effects of Bicalutamide include weakness, nausea, anemia (low red blood cell count), constipation, hot flashes, breathlessness, blood in urine, pain, infection, peripheral edema, diarrhea, and nocturia (increased urge to urinate during the night).

Expert Advice

  • You have been prescribed Bicalutamide for the treatment of prostate cancer.
  • Take it with or without food, preferably at the same time every day.
  • It may cause your skin to become light sensitive; avoid direct exposure to excessive sunlight.
  • Use sunscreen when outdoors.
  • If you are diabetic, monitor your blood glucose regularly while taking Bicalutamide.
  • Your doctor may want you to have regular blood tests to monitor your liver function while you are taking this medicine.
  • Inform your doctor if you notice any of the following symptoms:
    • Yellowing of eyes or skin
    • Dark urine
    • Stomach pain
  • Do not stop taking the medication without consulting your doctor first.
  • Do not drive or engage in activities requiring concentration until you know how Bicalutamide affects you.

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Frequently asked questions

Yes, Bicalutamide can cause diarrhea, though this side effect is rare; constipation is more common. Consult your doctor if diarrhea becomes a concern.
Bicalutamide should be taken at the same time every day, either in the morning or evening, as directed by your doctor.
Yes, hair loss is a common side effect of Bicalutamide, though it does not affect everyone. Consult your doctor if you are concerned about hair loss.
There is limited evidence to suggest that Bicalutamide causes infertility. While it has shown effects on fertility in animal studies, its impact on human fertility is assumed but not definitively proven. Some studies indicate it may affect spermatogenesis.
Bicalutamide is prescribed in combination with gonadotropin-releasing hormone (GnRH) agonists, like leuprolide or goserelin, to treat metastatic prostate cancer. It has also been used off-label for treating hirsutism in patients with polycystic ovarian disease.
No, Bicalutamide is not chemotherapy; it is an anti-androgen medication that blocks the effects of androgens (such as testosterone) to inhibit the growth and spread of cancer cells.
Bicalutamide should be taken continuously for at least 2 years or until the disease progresses. Do not discontinue use without consulting your doctor.
Patients taking Bicalutamide should avoid direct sun exposure, sunlamps, and tanning beds due to potential skin sensitivity. It is recommended to use sunscreen during treatment.
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