How Betamethasone, Clindamycin, and Nicotinamide Work Betamethasone, Clindamycin, and Nicotinamide is a combination of three medications: Betamethasone, Clindamycin, and Nicotinamide. Betamethasone is a steroid that works by blocking the production of certain chemical messengers in the body, which cause inflammation (redness and swelling) and allergies. Clindamycin is an antibiotic that prevents the synthesis of essential proteins required by bacteria to perform vital functions. This action stops the bacteria from growing and prevents the infection from spreading. Nicotinamide is a form of vitamin B that provides essential nutrients.
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