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Artemether + Lumefantrine

Uses

Artemether and Lumefantrine are used in the treatment of malaria.

How it Works

How Artemether and Lumefantrine work Artemether and Lumefantrine is a combination of two antiparasitic medicines that treat malaria. These medicines work by increasing the levels of heme in the blood, a substance toxic to the malarial parasite. This action kills the parasite and prevents the infection from spreading.

Side Effects

Common side effects of Artemether and Lumefantrine include headache, dizziness, weakness, joint pain, muscle pain, decreased appetite, fever, cough, vomiting, nausea, diarrhea, abdominal pain, palpitations, fatigue, general discomfort, hepatomegaly (enlarged liver), insomnia (difficulty sleeping), inflammation of the nose, rash, and itching.

Expert Advice

  • You have been prescribed Artemether + Lumefantrine for the treatment of acute uncomplicated malaria that is resistant to other antimalarial medications, such as chloroquine.
  • Tips to reduce the chance of being bitten by mosquitoes:
    • Wear light-colored and covered clothing when you are outside after sunset.
    • Use insect repellent creams or sprays on parts of your body not covered by clothing.
    • Spray to kill any mosquitoes that may have entered rooms despite screening.
  • Finish the prescribed course, even if you start to feel better. Stopping it early may cause the infection to return and become harder to treat.
  • Take the medication with food or drinks rich in fat, such as milk.
  • It may cause fatigue and dizziness; use caution while driving or performing tasks that require concentration.
  • If you vomit within 1 hour of taking the tablets, take another dose.
  • Inform your doctor if you have kidney, liver, or heart disease.

Other Combinations

Artesunate + Lumefantrine

Arteether + Lumefantrine

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Artemether 20mg + Lumefantrine 120mg

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Artemether 80mg + Lumefantrine 480mg

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Artemether 80mg + Lumefantrine 480mg

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Frequently asked questions

How should I take Artemether+Lumefantrine?
Take Artemether+Lumefantrine with food as prescribed by your doctor, typically twice a day for 3 days. On the first day, take the first dose with food, followed by the second dose 8 hours later. For the next 2 days, take one dose in the morning and one in the evening. Resuming normal eating as tolerated enhances the medicine's absorption.
What are the contraindications for Artemether+Lumefantrine?
Artemether+Lumefantrine is contraindicated in patients with known hypersensitivity to any of its ingredients. Caution is advised for patients with severe malaria and during the first trimester of pregnancy.
Is it safe to take Artemether+Lumefantrine during pregnancy?
No, Artemether+Lumefantrine is harmful during the first trimester of pregnancy as it increases the risk of fetal loss.
What are the storage and disposal instructions for Artemether+Lumefantrine?
Store Artemether+Lumefantrine in its original container, tightly closed, out of reach of children. Keep it at room temperature, away from excessive heat and moisture.
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