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Argatroban

Uses

Argatroban is used in the treatment of heart attacks and unstable angina.

How it Works

How Argatroban works Argatroban is a direct thrombin inhibitor. It functions by reversibly binding to thrombin, a substance in the blood responsible for blood clotting. This action prevents the formation of harmful clots in the body.

Side Effects

Common side effects of Argatroban include back pain, cardiac arrest, chest pain, decreased blood pressure, diarrhea, fever, headache, nausea, sepsis, breathlessness, vomiting, bleeding, blood clots, and anemia (low number of red blood cells).

Expert Advice

  • It is a hospital-only medication.
  • It is administered by your nurse or doctor as an infusion (drip) into a vein.
  • It increases your risk of bleeding.
  • Exercise caution while:
    • Shaving
    • Cutting fingernails or toenails
    • Using sharp objects
  • Notify your doctor if you notice:
    • Blood in your vomit
    • Blood in your urine
    • Stool that is black and tarry or contains bright red blood
  • Inform your doctor if you are taking:
    • Other blood thinners
    • Medications to prevent blood clots

Other Combinations

Related Medications

Frequently asked questions

While Argatroban is not commonly associated with hair loss compared to other blood thinners, there are rare reports of this side effect. Consult your doctor if you experience hair loss while on Argatroban to rule out other causes.
Patients with a known allergy to Argatroban, those experiencing unusual bleeding, individuals with artificial heart valves, and those with severe kidney disease should avoid this medication. Inform your doctor if you have had or plan to have heart valve replacement surgery.
Argatroban typically does not affect liver function, but long-term use may pose a risk of mild liver injury in patients with elevated liver enzymes. The risk is lower than with other anticoagulants. Inform your doctor if you have a history of liver disease before starting this medication.
Store Argatroban at room temperature between 20º and 25º C (68º-77°F) in its original packaging. Do not freeze, and keep it in a dry place away from moisture and light. Ensure it is kept out of reach of children.
It is advisable to avoid alcohol while taking Argatroban, as it may enhance the medication's effects and increase the risk of bleeding. Regular alcohol consumption can also lead to gastric ulcers, which may cause further bleeding. Consult your doctor if you experience any bleeding.
Yes, Argatroban can increase the risk of bleeding. Exercise caution during activities that may lead to injury and report any unusual bruising or bleeding to your doctor immediately.
You may not notice any immediate changes after starting Argatroban, as it works to reduce the risk of blood clots in various blood vessels. It is important to continue taking the medication as prescribed to achieve its full benefits.
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