Apremilast

Uses

Apremilast is used in the treatment of plaque psoriasis. It is indicated for patients who have had an inadequate response or have been intolerant to a previous medication.

How it Works

How Apremilast works Apremilast is a phosphodiesterase 4 (PDE4) inhibitor. It functions by blocking the action of specific chemical messengers that are responsible for inflammation associated with psoriatic arthritis and psoriasis, thereby reducing the signs and symptoms of these conditions.

Side Effects

Common side effects of Apremilast include diarrhea, nausea, vomiting, upper respiratory tract infection, headache, tension headache, bronchitis (inflammation of the airways), nasopharyngitis (inflammation of the throat and nasal passages), decreased appetite, insomnia (difficulty sleeping), depression, migraine, cough, dyspepsia, increased bowel movements, upper abdominal pain, gastroesophageal reflux disease, back pain, fatigue, tooth abscess, hair follicle inflammation, and joint pain.

Expert Advice

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