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Apixaban

Uses

Apixaban is used for stroke prevention, as well as the prevention of deep vein thrombosis and pulmonary embolism. It works by preventing the formation of blood clots in the legs, lungs, brain, or heart.

How it Works

How Apixaban works Apixaban is a novel oral anticoagulant (NOAC) that prevents the formation of blood clots in the body.

Side Effects

Common side effects of Apixaban include anemia (low red blood cell count), blood in urine, bruising, nausea, nosebleeds, and hematoma.

Expert Advice

  • Apixaban is an effective medication for preventing blood clots.
  • Apixaban can be taken with or without food.
  • Nighttime administration is not preferred.
  • It has minimal interactions with food and other medications, so frequent dose adjustments are not necessary.
  • Apixaban increases your risk of bleeding; exercise caution while:
    • Shaving
    • Cutting fingernails or toenails
    • Using sharp objects
    • Engaging in contact sports (e.g., football, wrestling)
  • If you are scheduled for surgery or dental treatment, you may be advised to temporarily discontinue Apixaban.
  • Inform your doctor if you notice blood in your vomit, urine, or stool (e.g., black, tarry stools or bright red blood).
  • Notify your doctor if you have any kidney issues.
  • Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
  • Do not stop taking the medication without consulting your doctor.

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Frequently asked questions

Yes, if you have difficulty swallowing, you may crush the tablet and mix it with water, 5% dextrose in water, apple juice, or apple puree. Crush it just before taking it.
Apixaban is used to lower the risk of stroke and blood clots in individuals with atrial fibrillation, as well as to prevent and treat blood clots in the legs (DVT) and lungs (pulmonary embolism), especially after hip or knee replacement surgery.
Symptoms of an overdose may include unusual bleeding or bruising, red, brown, or pink urine, red or black tarry stools, and coughing up or vomiting blood or coffee ground-like material. Seek immediate medical attention if these occur.
Yes, Apixaban is an anticoagulant, commonly referred to as a blood thinner, which works by inhibiting factor Xa to prevent blood clotting.
Consult your doctor regarding whether to stop Apixaban prior to surgery. If the procedure poses a moderate to high bleeding risk, you may need to discontinue it 48 hours beforehand.
Apixaban can increase the risk of excessive bleeding. Do not discontinue use without consulting your doctor. If you undergo epidural or spinal procedures while on Apixaban, inform your doctor, as this could increase the risk of spinal blood clots and potential paralysis.
Take the missed dose of Apixaban as soon as you remember, then continue with your regular twice-daily schedule.
Common side effects include bleeding (in the eyes, stomach, nose, etc.), anemia (leading to tiredness or paleness), low blood pressure (causing faintness or rapid heartbeat), and nausea. Blood tests may indicate elevated gamma glutamyltransferase (GGT), potentially signaling liver issues.
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