Apalutamide

Uses

Apalutamide is used in the treatment of cancer, including prostate cancer, polycystic ovarian syndrome (PCOS), and excessive hair growth.

How it Works

How Apalutamide works Prostate cancer cells rely on androgens for growth and survival. Even when the cancer becomes resistant to standard hormonal therapies, such as castration-resistant cases, androgen receptors in the cancer cells remain active and continue to promote cancer growth. Apalutamide targets these androgen receptors, blocking their activation and preventing them from binding to androgens. This action inhibits the signaling pathway that drives the growth and proliferation of prostate cancer cells.

Side Effects

Common side effects of Apalutamide include fatigue, skin rash, high blood pressure, flushing (a sense of warmth in the face, ears, neck, and trunk), joint pain, diarrhea, falls, and weight loss.

Expert Advice

If you have ever experienced a seizure, you must inform your doctor.
If you have a history of brain injury, stroke (within the past year), or primary brain tumor, notify your doctor.
Inform your doctor if you have a history of cardiovascular problems.
Follow your doctor's instructions regarding the dosage, timing, and duration of your treatment.
Attend all follow-up visits with your doctor as scheduled.
Your doctor may monitor your liver function while you are on Apalutamide treatment, as it can affect liver enzymes.
You have been prescribed Apalutamide for the treatment of prostate cancer.
Take it with or without food, preferably at the same time every day.
Do not drive or engage in activities requiring concentration until you know how Apalutamide affects you.
Apalutamide may cause your skin to become light sensitive.
Avoid direct exposure to excessive sunlight and use sunscreen when outdoors.
If you are diabetic, monitor your blood glucose regularly while taking Apalutamide.
Your doctor may require regular blood tests to monitor your liver function while you are taking this medication.
Inform your doctor if you notice yellowing of the eyes or skin, dark urine, or abdominal pain.
Do not stop taking the medication without consulting your doctor first.