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Anastrozole

Uses

Anastrozole Uses Anastrozole is used in the treatment of breast cancer. It is administered alongside other treatments, such as surgery or radiation, for women who have reached menopause.

How it Works

How Anastrozole works Anastrozole is an aromatase inhibitor that functions by reducing the amount of estrogen, a natural female hormone, produced in the body. This reduction can inhibit or halt the growth of certain breast cancer cells that rely on estrogen for their growth.

Side Effects

Common side effects of Anastrozole include headache, nausea, osteoporosis, weakness, diarrhea, hypercholesterolemia (high cholesterol), joint inflammation, joint pain, muscle pain, rash, vaginal bleeding, vaginal dryness, vomiting, decreased appetite, sleepiness, carpal tunnel syndrome, sensory disturbance, hot flushes, increased alkaline phosphatase level in the blood, increased alanine aminotransferase, increased aspartate aminotransferase, hair loss, allergic reaction, and bone pain.

Expert Advice

  • Anastrozole is used for the treatment of hormone-dependent breast cancer in postmenopausal women.
  • Take it at the same time every day.
  • It may cause weakness and sleepiness.
  • Do not drive or engage in activities requiring concentration until you know how it affects you.
  • Nausea may occur when starting treatment with this medicine but should diminish over time.
  • If nausea is bothersome, take it after a meal.
  • Your doctor may regularly check your Vitamin D levels and bone mineral density, and suggest supplements if needed.
  • Do not take Anastrozole if you are pregnant or breastfeeding.

Other Combinations

Frequently asked questions

Anastrozole can cause hair thinning and potential hair loss, although this does not occur in everyone. This effect is likely due to the drug's estrogen-lowering impact and is usually not permanent. If you are concerned, discuss alternative medications with your doctor.
Anastrozole can be taken at any time of day as prescribed by your doctor, with or without food. Do not crush, break, or chew the tablet.
Anastrozole may cause weight gain, though it is uncommon. Other factors, such as menopause, may also contribute. If you gain weight while on Anastrozole, consider a low-calorie diet and regular exercise, and consult your doctor or a nutritionist for assistance.
Bodybuilders use Anastrozole to mitigate estrogen production, a side effect of anabolic steroid use. Elevated estrogen can lead to undesirable traits such as voice changes, testicular shrinkage, and breast enlargement, which Anastrozole helps prevent.
Anastrozole should not be used with tamoxifen, as it may reduce its effectiveness. Additionally, medications containing estrogen, such as birth control pills, creams, vaginal rings, and suppositories, can interfere with Anastrozole's action.
Patients taking Anastrozole should have regular blood tests to monitor blood cell counts and liver and kidney function. A bone scan may also be recommended if there is a risk of osteoporosis.
Contact your doctor if you experience serious side effects, such as prolonged nausea, severe vomiting, extreme weakness, or significant pain. Additionally, inform your doctor if you exceed the recommended dosage of Anastrozole.
Anastrozole can increase the risk of heart disease, particularly in women with early breast cancer and existing heart artery blockages. Seek medical attention if you experience shortness of breath or new or worsening chest pain.
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