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Acalabrutinib

Uses

Acalabrutinib is used in the treatment of blood cancer.

How it Works

Acalabrutinib works by inhibiting the action of an abnormal protein that promotes the proliferation of cancer cells. This mechanism helps to prevent the spread of cancer cells.

Side Effects

Common side effects of Acalabrutinib include anemia (low red blood cell count), decreased white blood cell count (neutrophils), upper respiratory tract infection, low platelet count, headache, diarrhea, and musculoskeletal pain (bone, muscle, or joint pain).

Expert Advice

Before taking Acalabrutinib, inform your doctor about all other medications, including:

Prescription medications
Over-the-counter medications
Vitamins
Herbal remedies

Avoid using antacids within 2 hours of taking this medicine.
You may be at risk of infection; therefore, try to:

Avoid crowds
Stay away from individuals with colds
Immediately report fever or any other signs of infection to your doctor

Avoid sun exposure. Ensure to:

Wear SPF 15 (or higher) sunblock
Use protective clothing

Drink plenty of water every 24 hours after starting treatment.
Consume foods that may help reduce diarrhea and ensure adequate rest.
Avoid contact sports or situations where you may bruise or get injured, as this medicine increases the risk of bleeding.
Inform your doctor about any planned surgeries or dental procedures while taking Acalabrutinib.

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Frequently asked questions

Can Acalabrutinib be taken with obinutuzumab?

Please consult your healthcare provider for specific guidance regarding the combination of Acalabrutinib and obinutuzumab.

How can I relieve diarrhea while taking Acalabrutinib?

To relieve diarrhea, consume foods high in soluble fiber, such as ripe bananas, oranges, boiled potatoes, white rice, curd, and oatmeal. Stay hydrated by drinking 8-10 glasses of water daily and consider soups and juices for additional hydration.

Why am I experiencing gum bleeding after brushing my teeth?

Bleeding from the gums may result from a decrease in platelet count, which are essential for blood clotting.

Should I avoid certain foods and drinks while on Acalabrutinib?

Generally, you can maintain your normal diet unless advised otherwise by your doctor. It is recommended to sip water regularly to prevent dehydration, eat small nourishing snacks frequently, and use hard candy or popsicles to help prevent nausea and vomiting.

What should I do about skin changes after taking Acalabrutinib?

To manage rashes and dry, itchy skin, use a moisturizer, avoid direct sunlight, wear protective clothing, and apply sunscreen with SPF over 15 outdoors. Refrain from swimming if you have a rash, avoid hot baths, and wear loose, cotton clothing. Skin conditions typically improve after stopping treatment.

What tests are conducted before and during Acalabrutinib treatment?

Your doctor will order blood tests to monitor your blood cell levels and assess liver and kidney function.

Are nausea and extreme tiredness common side effects of Acalabrutinib?

Yes, nausea and fatigue are common side effects of Acalabrutinib. To alleviate nausea, eat smaller, more frequent meals and avoid salty, spicy, fried, or fatty foods. Ensure you rest adequately and engage in light exercise to help reduce fatigue.

How can I cope with tiredness and weakness after starting Acalabrutinib?

Gentle exercise can help reduce tiredness, but consult your doctor before starting any exercise regimen.

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