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Nortriptyline 10mg + Pregabalin 75mg

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Prezal-NT Tablet
Prezal-NT Tablet
Prezal-NT Tablet

Prezal-NT Tablet

Galanthus Pharma Pvt. Ltd.

Strip of 10 tablets

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Used In

Treatment of Neuropathic pain

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More About Prezal-NT

Benefits
Side Effects
How to use
How it works
What if I forget to take it?
Manufacturer Address

Benefits

Treatment of Neuropathic painTreatment of Neuropathic pain

In Treatment of Neuropathic pain : Prezal-NT Tablet is a combination of medicines used to treat long-lasting (chronic) pain caused by nerve damage due to diabetes, shingles, or spinal cord injury. It reduces pain and its associated symptoms such as mood changes, sleep problems, and tiredness. It is thought to work by interfering with pain signals that travel through the damaged nerves and the brain. Taking Prezal-NT Tablet regularly will improve your physical and social functioning and overall quality of life. It takes a few weeks to work so you need to take it regularly even if you feel it is not doing any good. Once your symptoms have gone you should still keep taking the medicine until your doctor advises you to stop.In Treatment of Neuropathic pain : Prezal-NT Tablet is a combination of medicines used to treat long-lasting (chronic) pain caused by nerve damage due to diabetes, shingles, or spinal cord injury. It reduces pain and its associated symptoms such as mood changes, sleep problems, and tiredness. It is thought to work by interfering with pain signals that travel through the damaged nerves and the brain. Taking Prezal-NT Tablet regularly will improve your physical and social functioning and overall quality of life. It takes a few weeks to work so you need to take it regularly even if you feel it is not doing any good. Once your symptoms have gone you should still keep taking the medicine until your doctor advises you to stop.

Side Effects

Side effects of Prezal-NT Tablet The majority of side effects typically do not necessitate medical intervention. and disappear as your body adjusts to the medicine. Doctor consultation is advised if they persist or if you�re worried about them Common side effects of Prezal-NTConstipation Difficulty in urination Weight gain Sleepiness Dizziness Tiredness Blurred vision Dryness in mouth Increased heart rate Uncoordinated body movements Orthostatic hypotension (sudden lowering of blood pressure on standing)Increased appetite Increased libido Paresthesia (tingling or pricking sensation)Vertigo VomitingSide effects of Prezal-NT Tablet The majority of side effects typically do not necessitate medical intervention. and disappear as your body adjusts to the medicine. Doctor consultation is advised if they persist or if you�re worried about them Common side effects of Prezal-NTConstipation Difficulty in urination Weight gain Sleepiness Dizziness Tiredness Blurred vision Dryness in mouth Increased heart rate Uncoordinated body movements Orthostatic hypotension (sudden lowering of blood pressure on standing)Increased appetite Increased libido Paresthesia (tingling or pricking sensation)Vertigo Vomiting

How to use

How to use Prezal-NT Tablet Follow your doctor's guidance regarding the dose and duration of this medication. Ingest it without breaking or crushing. Do not chew, crush or break it. Prezal-NT Tablet can be taken it with or without food, although it's advisable to take it consistently at the same time.How to use Prezal-NT Tablet Follow your doctor's guidance regarding the dose and duration of this medication. Ingest it without breaking or crushing. Do not chew, crush or break it. Prezal-NT Tablet can be taken it with or without food, although it's advisable to take it consistently at the same time.

How it works

How Prezal-NT Tablet works Prezal-NT Tablet is a combination of two medicines: Pregabalin and Nortriptyline. Pregabalin is an alpha 2 delta ligand which decreases the pain by modulating calcium channel activity of the nerve cells. Nortriptyline is a tricyclic antidepressant which increases the levels of chemical messengers (serotonin and noradrenaline) that stop the movement of pain signals in the brain. Together, they relieve neuropathic pain (pain from damaged nerves).How Prezal-NT Tablet works Prezal-NT Tablet is a combination of two medicines: Pregabalin and Nortriptyline. Pregabalin is an alpha 2 delta ligand which decreases the pain by modulating calcium channel activity of the nerve cells. Nortriptyline is a tricyclic antidepressant which increases the levels of chemical messengers (serotonin and noradrenaline) that stop the movement of pain signals in the brain. Together, they relieve neuropathic pain (pain from damaged nerves).

Alcohol

Not Safe: Consuming alcohol with Prezal-NT Tablet may lead to excessive drowsiness.Not Safe: Consuming alcohol with Prezal-NT Tablet may lead to excessive drowsiness.

Pregnancy

Prezal-NT Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Doctor consultation is advised.Prezal-NT Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Doctor consultation is advised.

Breast feeding

Prezal-NT Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.Prezal-NT Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

Prezal-NT Tablet may cause side effects which could affect your ability to drive.As Prezal-NT Tablet may affect your alertness which may affect your ability to drive.Prezal-NT Tablet may cause side effects which could affect your ability to drive.As Prezal-NT Tablet may affect your alertness which may affect your ability to drive.

Kidney

Prezal-NT Tablet should be used with caution in patients with kidney disease. Dose adjustment of Prezal-NT Tablet may be needed. Doctor consultation is advised.Prezal-NT Tablet should be used with caution in patients with kidney disease. Dose adjustment of Prezal-NT Tablet may be needed. Doctor consultation is advised.

Liver

Prezal-NT Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Prezal-NT Tablet may not be needed in these patients. Please consult your doctor.Prezal-NT Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Prezal-NT Tablet may not be needed in these patients. Please consult your doctor.

What if I forget to take it?

If a dose of Prezal-NT Tablet is missed, take it promptly. However, if your next dose is approaching, skip the missed dose and resume your regular schedule. Avoid doubling the dose.If a dose of Prezal-NT Tablet is missed, take it promptly. However, if your next dose is approaching, skip the missed dose and resume your regular schedule. Avoid doubling the dose.

Manufacturer Address

707 Vidyapati Nagar Indra Enclave, New Delhi-110086

Frequently asked questions

Prezal NT Tablet is a combination of Pregabalin and Nortriptyline, used to treat nerve pain by calming overactive nerves and reducing pain sensation.
Regular check-ups may be necessary after starting Prezal NT Tablet. Consult your doctor if symptoms persist or side effects interfere with daily life.
If you miss a dose, take it as soon as you remember unless it's close to the next dose. Do not double up to make up for a missed dose.
Initial benefits may be seen after 2 weeks, but full effects can take 2-3 months or longer.
Contact your doctor or seek emergency help immediately, even without symptoms. Overdose symptoms can include drowsiness, confusion, and breathing difficulties.
Prezal NT Tablet can impact sexual function, causing decreased desire, erectile dysfunction, and difficulty reaching orgasm. Discuss any issues with your doctor.
No, continue taking Prezal NT Tablet as prescribed by your doctor to avoid withdrawal symptoms. Gradually taper the dose if you need to stop.
Yes, Prezal NT Tablet can cause drowsiness or sudden sleep episodes. Avoid driving or operating machinery until you know how it affects you.
Avoid alcohol, grapefruit, and activities requiring alertness. Protect yourself from sunlight as Prezal NT Tablet can increase sunburn risk.
Prezal NT Tablet may increase hunger, leading to weight gain. To prevent this, maintain a balanced diet, avoid high-calorie foods, and exercise regularly.
Serious side effects are rare but can include breathing difficulties, increased heartbeat, mood changes, and signs of infection. Seek medical attention if these occur.
Store Prezal NT Tablet in its original packaging in a cool, dry place, out of reach of children. Dispose of unused medications safely.
No, higher doses do not increase effectiveness and may lead to serious side effects. Consult your doctor if symptoms worsen.

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References

  • Pregabalin (22 Apr. 2019)

  • Pregabalin (22 Apr. 2019)

  • Pregabalin and Nortriptyline (28th Sept. 2023)

  • Pregabalin+Nortriptyline (28th Sept. 2023)

  • Nortriptyline (14 Apr. 2025)

Disclaimer

PlatinumRx is dedicated to delivering dependable and trustworthy information to empower our customers. However, the information presented here is solely for general informational purposes and should not be utilized for diagnosing, preventing, or treating health issues. It is not intended to establish a doctor-patient relationship or serve as a substitute for professional medical advice.

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