Slipizem 5mg Suppository belongs to a class of medicines known as benzodiazepines. It is used to treat increased episodes of seizures in people who are already under the treatment for epilepsy (seizures or fits). This medicine is used for short term treatment of seizure attacks. Slipizem 5mg Suppository alters brain activity, calms it and provides relief from seizures (fits) by relaxing the nerves. It is given under the supervision of a healthcare professional and it is inserted into the rectum. Take this medicine in the dose and duration as advised by your doctor as it has a high potential of habit-forming. If you have missed a dose, take it as soon as you remember it and finish the full course of treatment even if you feel better. Do not stop taking it suddenly without talking to your doctor as it may cause nausea and anxiety. This medicine is generally well tolerated with minimal or no side effects but it may cause slight rectal discomfort. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Pregnant and breastfeeding mothers should consult their doctor before taking it. If you have been taking this medicine for a long time then regular monitoring of blood and liver functions may be required.
Written by: Radhika B Shiraguppi, B. Pharma
Reviewed by: Dr. Jay Faldu, MBBS
Last updated on: 13-04-2024
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Slipizem 5mg Suppository belongs to a class of medicines known as benzodiazepines. It is used to treat increased episodes of seizures in people who are already under the treatment for epilepsy (seizures or fits). This medicine is used for short term treatment of seizure attacks. Slipizem 5mg Suppository alters brain activity, calms it and provides relief from seizures (fits) by relaxing the nerves. It is given under the supervision of a healthcare professional and it is inserted into the rectum. Take this medicine in the dose and duration as advised by your doctor as it has a high potential of habit-forming. If you have missed a dose, take it as soon as you remember it and finish the full course of treatment even if you feel better. Do not stop taking it suddenly without talking to your doctor as it may cause nausea and anxiety. This medicine is generally well tolerated with minimal or no side effects but it may cause slight rectal discomfort. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Pregnant and breastfeeding mothers should consult their doctor before taking it. If you have been taking this medicine for a long time then regular monitoring of blood and liver functions may be required.
Epilepsy/Seizures
In Epilepsy/Seizures Slipizem 5mg Suppository slows down electrical signals in the brain which cause seizures (fits). It can also help reduce symptoms such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety. The medicine can allow you to do some activities that you would otherwise be forbidden or scared to do (such as swimming and driving). It can take a few weeks for this medicine to work (because the dose has to be increased slowly) and during this time you may still have seizures. It is inserted into the rectum by a doctor or nurse. Follow your doctor?s instructions carefully.
The majority of side effects typically do not necessitate medical intervention. and disappear as your body adjusts to the medicine. Doctor consultation is advised if they persist or if you're worried about them.
Remove the wrapper from the suppository before inserting it. Keep lying down for about 15 minutes after insertion so that the suppository does not come out before it melts.
Slipizem 5mg Suppository is a benzodiazepine (BZD). It is absorbed rapidly into the bloodstream from the rich blood supply of the rectal area. Once absorbed, it quickly increases the action of GABA, a chemical messenger. This action suppresses the abnormal and excessive activity of the nerve cells in the brain, thereby controlling seizures.
Pregnancy
Seek medical advice from your doctor: Slipizem 5mg Suppository is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Doctor consultation is advised.
Breast feeding
Seek medical advice from your doctor: Slipizem 5mg Suppository is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Kidney
Caution Advised: Slipizem 5mg Suppository should be used with caution in patients with kidney disease. Dose adjustment of Slipizem 5mg Suppository may be needed. Doctor consultation is advised. Dose adjustment may be required if it is to be given for a long period
Liver
Caution Advised: Slipizem 5mg Suppository should be used with caution in patients with liver disease. Dose adjustment of Slipizem 5mg Suppository may be needed. Doctor consultation is advised.
If a dose of Slipizem 5mg Suppository is missed, take it promptly. However, if your next dose is approaching, skip the missed dose and resume your regular schedule. Avoid doubling the dose.
Store in a cool and dry place, and keep the temperature below 30�C
Bliss GVS Pharma Ltd., 102,Hyde Park, Saki Vihar Road, Andheri (East),Mumbai ‚ 400072, India
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