Myelosafe PG Tablet belongs to a group of medicines that affect how your immune system works. $It is used in the treatment of multiple myeloma and myelodysplastic syndrome. Myelosafe PG Tablet can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.Some common side effects of this medicine include headache, weakness, nausea, rash, and dizziness amongst others. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections or bleeding. Hence, take caution while performing the activity that might increase your chances of bleeding or avoid contact with people suffering from an infection such as a cold. Regular blood tests are required to check your blood cells while on treatment.Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You are advised to drink plenty of fluids to stay hydrated while taking this medicine.
Written by: Radhika B Shiraguppi, B. Pharma
Reviewed by: Dr. Jay Faldu, MBBS
Last updated on: 31-05-2025
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Myelosafe PG Tablet belongs to a group of medicines that affect how your immune system works. $It is used in the treatment of multiple myeloma and myelodysplastic syndrome. Myelosafe PG Tablet can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.Some common side effects of this medicine include headache, weakness, nausea, rash, and dizziness amongst others. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections or bleeding. Hence, take caution while performing the activity that might increase your chances of bleeding or avoid contact with people suffering from an infection such as a cold. Regular blood tests are required to check your blood cells while on treatment.Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You are advised to drink plenty of fluids to stay hydrated while taking this medicine.
Treatment of Multiple myeloma / Treatment of Myelodysplastic syndrome
In Treatment of Multiple myeloma : If you have multiple myeloma, your body is destroying bone faster than it is being replaced. This makes bones weak and painful and more likely to break. Myelosafe PG Tablet may be prescribed along with other cancer treatments such as chemotherapy. It is an important part of your treatment and increases the survival rate of people with multiple myeloma. This medicine will kill the cancerous cells and prevent their further growth as well as spread to other parts of the body. Follow your doctor�s instructions carefully to get the most benefit. Supplements of calcium and Vitamin D3 are also effective and may be prescribed if you do not have high blood calcium levels.In Treatment of Myelodysplastic syndrome Myelodysplastic Syndromes (MDS) are a group of rare blood disorders characterized by abnormal development of blood cells in the bone marrow. In MDS, the bone marrow fails to produce enough healthy and fully matured blood cells, leading to low blood cell counts, which can result in anemia, infections, and bleeding problems.Myelosafe PG Tablet is used to treat certain types of MDS, specifically those associated with a specific part of the chromosomes in the blood cells. It works by helping the immune system make more healthy blood cells in the bone marrow. Myelosafe PG Tablet helps improve the production of red blood cells, reducing the need for frequent blood transfusions and making them feel better. It is important to check-up and monitor regularly to make sure it is safe and effective.show moreshow less
Side effects of Myelosafe PG Tablet The majority of side effects typically do not necessitate medical intervention. and disappear as your body adjusts to the medicine. Doctor consultation is advised if they persist or if you�re worried about them Common side effects of Myelosafe PGHeadache Nausea Rash Breathlessness Dizziness Fatigue Decreased white blood cell count (neutrophils)Joint pain Itching Diarrhea Low blood platelets Peripheral edema Cough Back pain Upper respiratory tract infection
How to use Myelosafe PG Tablet Follow your doctor's guidance regarding the dose and duration of this medication. Ingest it without breaking or crushing. Do not chew, crush or break it. Myelosafe PG Tablet can be taken it with or without food, although it's advisable to take it consistently at the same time.
How Myelosafe PG Tablet works Myelosafe PG Tablet is an anti-cancer medication. It works by enhancing the immune system that indirectly attacks the cancer cells. It prevents the growth of new blood vessels within the tumor. It also restricts the production of chemical messengers (cytokine and growth factor) which are responsible for the growth of cancer cells. This is how it works against cancer.
Alcohol
Consult your Doctor: Please consult your doctor regarding the safety of consuming alcohol with Myelosafe PG Tablet . Experts have not found evidence of alcohol impairing the effectiveness of the medicine.
Pregnancy
Myelosafe PG Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
Myelosafe PG Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
Myelosafe PG Tablet may cause side effects which could affect your ability to drive.You may feel dizzy, tired, sleepy, have vertigo or blurred vision after taking Myelosafe PG Tablet and this may affect your ability to drive.
Kidney
Myelosafe PG Tablet should be used with caution in patients with kidney disease. Dose adjustment of Myelosafe PG Tablet may be needed. Doctor consultation is advised.
Liver
Myelosafe PG Tablet should be used with caution in patients with liver disease. Dose adjustment of Myelosafe PG Tablet may be needed. Doctor consultation is advised.
If a dose of Myelosafe PG Tablet is missed, take it promptly. However, if your next dose is approaching, skip the missed dose and resume your regular schedule. Avoid doubling the dose.
Store in a cool and dry place, and keep the temperature below 30�C
You may be monitored with regular blood tests before and during the treatment as lenalidomide may cause a fall in the white blood cells and platelets, required to fight infection, Hemoglobin and blood clotting. Avoid activities that may cause bruising or injury and avoid contact with people who have colds or infections. It makes your skin sensitive towards sunlight. Apply sunscreen or wear protective while going out.� It may cause dehydration. Drink plenty of water to stay hydrated while taking medication. �It is not recommended for use in children and adolescents under 18 years. You should use proper contraceptive methods at least 4 weeks before, during and until 4 weeks after stopping treatment.� Woman of childbearing potential will be required to undergo pregnancy tests before and after the treatment. You should inform your doctor or dentist that you are taking Myelosafe PG Tablet before you receive any medical or dental care, emergency care, or surgery. It may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you. You may be at risk of developing acute myelogenous leukemia, fatal liver problems, severe skin reactions, and fatal heart problems during treatment with Myelosafe PG Tablet. You should discuss in advance the benefits and risks of taking this medicine.
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